The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Transcutaneous analyte sensor

A surgical instrument can be disinfected or sterilized, and has a rechargeable secondary battery incorporated therein. A distal treatment section of the surgical instrument is ultrasonically oscillated or otherwise activated using the secondary battery as a driving power source to perform surgery on a living tissue. Electromagnetic energy generated by an energy generation unit located outside the surgical instrument is received by a reception coil incorporated in the surgical instrument with the surgical instrument by induction from the energy generation unit. The electromagnetic energy is then converted into charging power with which the secondary battery is recharged. Thus, the surgical instrument can be readily recharged without compromising sterility.

Surgical apparatus permitting recharge of battery-driven surgical instrument in noncontact state

A repeater device for an advanced patient management system communicates with a medical device coupled to a patient to obtain data about the medical device and/or patient's condition. The repeater device maintains the data while if considers various factors when coordinating transfer of the data to a repository of the advanced patient management system. The repeater device may be configured to analyze the data to determine a degree of urgency, such as whether an emergency exists, and then determine when to transfer the data based on the degree of urgency. The repeater device may also be configured to test the condition of the communication medium being used to transfer the data to the repository, such as determining whether a telephone line is in use, and then determine when to transfer the data based on the condition of the of the communication medium.

Repeater device for communications with an implantable medical device

Methods of monitoring and evaluating the status of a tumor undergoing treatment includes monitoring in vivo at least one physiological parameter associated with a tumor in a subject undergoing treatment, transmitting data from an in situ located sensor to a receiver external of the subject, analyzing the transmitted data, repeating the monitoring and transmitting steps at sequential points in time and evaluating a treatment strategy. The method provides dynamic tracking of the monitored parameters over time. The method can also include identifying in a substantially real time manner when conditions are favorable for treatment and when conditions are unfavorable for treatment and can verify or quantify how much of a known drug dose or radiation dose was actually received at the tumor. The method can include remote transmission from a non-clinical site to allow oversight of the tumor's condition even during non-active treatment periods (in between active treatments). The disclosure also includes monitoring systems with in situ in vivo biocompatible sensors and telemetry based operations and related computer program products.

Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors

An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver/hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and/or via wireless communication.

Integrated medicament delivery device for use with continuous analyte sensor

In one embodiment described in the specification, a surgically implantable reciprocating pump employs a check valve as the piston, which is driven by a permanent magnet linear electric motor to assist either side of the natural heart The pump is implanted in the aorta or pulmonary artery using vascular attachment cuffs such as flexible cuffs for suturing at each end with the pump output directly in line with the artery The pump is powered by surgically implanted rechargeable batteries In another embodiment, pairs of pumps are provided to replace or assist the natural heart or to provide temporary blood flow throughout the body, for example, during operations to correct problems with the natural heart

Implantable device monitoring arrangement and method

Reciprocating pump circulatory assist arrangement

In one embodiment described in the specification, a surgically implantable reciprocating pump employs a check valve as the piston, which is driven by a permanent magnet linear electric motor to assist either side of the natural heart. The pump is implanted in the aorta or pulmonary artery using vascular attachment cuffs such as flexible cuffs for suturing at each end with the pump output directly in line with the artery. The pump is powered by surgically implanted rechargeable batteries. In another embodiment, pairs of pumps are provided to replace or assist the natural heart or to provide temporary blood flow throughout the body, for example, during operations to correct problems with the natural heart.

Surgically implantable power supply

Reciprocating pump and linear motor arrangement

Artificial heart and method of maintaining blood flow

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