James R. Davie
University of Manitoba
213 Papers
3.2K Citations
James R. Davie is an academic researcher from University of Manitoba. The author has contributed to research in topics: Chromatin & Histone code. The author has an hindex of 63, co-authored 204 publications. Previous affiliations of James R. Davie include University of A Coruña & Duke University.
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Papers
Covalent modifications of histones: expression from chromatin templates.
TL;DR: Transcription factors loaded onto regulatory DNA elements may recruit either coactivators with histone acetyltransferase activity or corepressors associated with hist one deacetylases.
222
Ubiquitination of Histone H3 in Elongating Spermatids of Rat Testes
TL;DR: The levels of ubiquitination of specific histones in meiotic and postmeiotic germ cells in rat testes by two-dimensional gel electrophoresis are characterized and it is speculated that its ubiquitinations could loosen the nucleosome structure in preparation for histone removal.
173
Control of histone modifications.
TL;DR: A new and exciting development, presented in this review, is the role of signal transduction pathways in the phosphorylation of histone H3 and the expression of immediate‐early genes.
154
Activation and function of immediate-early genes in the nervous system.
TL;DR: This review focuses on the immediate-early genes encoding transcription factors (AP-1 and Egr) that are relevant for neuronal responses and the current understanding of the mechanisms involved in the induction of these genes is presented.
152
The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes
Tasnim H. Beacon,Geneviève P. Delcuve,Camila López,Gino Nardocci,Igor Kovalchuk,Andre J. van Wijnen,James R. Davie +6 more
TL;DR: The broad epigenetic domain has a dynamic chromatin structure which supports frequent transcription bursts as discussed by the authors and is associated with a plethora of histone modifications (e.g., H3 acetylated at K27).