James Patrick Connell
Dow AgroSciences
10 Papers
84 Citations
James Patrick Connell is an academic researcher from Dow AgroSciences. The author has contributed to research in topics: Gene & Transgene. The author has an hindex of 5, co-authored 10 publications.
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Papers
Zinc finger nuclease-mediated transgene deletion
Joseph F. Petolino,Andrew F Worden,Krisi Curlee,James Patrick Connell,Tonya Strange Moynahan,Cory M Larsen,Sean M. Russell +6 more
TL;DR: Since ZFNs can be designed to bind and cleave a wide range of DNA sequences, these results constitute a general strategy for creating targeted gene deletions.
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Transcriptional activation of Brassica napus β‐ketoacyl‐ACP synthase II with an engineered zinc finger protein transcription factor
Manju Gupta,Russell Dekelver,Asha M. Palta,Carla Clifford,Sunita Gopalan,Jeffrey C. Miller,Stephen Novak,Daniel DeSloover,Daniel J Gachotte,James Patrick Connell,Josh Flook,Thomas G. Patterson,Kelly R. Robbins,Edward J. Rebar,Philip D. Gregory,Fyodor D. Urnov,Joseph F. Petolino +16 more
TL;DR: It is demonstrated that designed ZFP-TFs can be used to regulate the expression of endogenous genes to elicit specific phenotypic modifications of agronomically relevant traits in a crop species.
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Cotton alpha-globulin promoter: isolation and functional characterization in transgenic cotton, Arabidopsis, and tobacco.
TL;DR: Results show that the putative promoter region of cotton α-globulin B gene is highly tissue-specific and it can be used to control transgene expression in dicot seeds.
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A comprehensive study of the use of a homologous promoter in antisense cotton lines exhibiting a high seed oleic acid phenotype.
Ganesan Sunilkumar,LeAnne M. Campbell,Monjur Hossen,James Patrick Connell,Ernesto Hernandez,Avutu S. Reddy,Carl W. Smith,Keerti S. Rathore +7 more
TL;DR: Investigation of the ability of a promoter from a gene encoding a major storage protein in cottonseed to drive an antisense sequence of the cotton FAD2 gene to down-regulate the activity of Delta-12 desaturase enzyme in cottonseeds showed results that will be useful in the design of strategies to alter biosynthetic pathways for nutritional quality improvements and for the production of heterologous proteins of commercial value in seeds.
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Patent
Nucleic acid compositions conferring disease resistance
Vipula K. Shukla,Holly Jean Butler,Woosley Aaron T,Pamela Rene Haygood,Cristie M. Dewes,James Patrick Connell,Ignacio Larrinua,Avutu Sambi Reddy,Anthony Thinh Ngoc Trieu,Zihua Hu +9 more
- 30 Aug 2002
TL;DR: In this paper, the identification and isolation of genes that confer disease control properties in plants, as well as plants comprising such genes are derived from the following sources: Nicotiana benthamiana, Oryzae sativa (var. Indica IR7), Papaver rhoeas, Saccharomyces cerevisiae and Trichoderma harzianum.
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