James Moore
City of Hope National Medical Center
13 Papers
219 Citations
James Moore is an academic researcher from City of Hope National Medical Center. The author has contributed to research in topics: Photodynamic therapy & Medicine. The author has an hindex of 11, co-authored 13 publications.
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Papers
Oral administration of dihydroartemisinin and ferrous sulfate retarded implanted fibrosarcoma growth in the rat.
James Moore,Henry Lai,Jian-Ren Li,Ru-Long Ren,J.A. McDougall,Narendra P. Singh,Chung-Kwang Chou +6 more
TL;DR: It was found that the growth rate of the tumor was significantly retarded by daily oral administration of ferrous sulfate followed by dihydroartemisinin, suggesting that an artemisin in analog-ferrous salt combination may provide a novel approach for cancer therapy.
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Interstitial photodynamic therapy in the canine prostate
TL;DR: Interstitial PDT in the canine prostate using Photofrin produced modest volumes of tissue necrosis, and the minimum light dose required to induce necrosis was variable because bleeding was unpredictable in relation to the optical fibre.
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Photodynamic therapy for superficial bladder cancer under local anaesthetic
David C Shackley,C.H. Briggs,A Gilhooley,Colin Whitehurst,Kieran O’Flynn,C D Betts,James Moore,Noel W. Clarke +7 more
TL;DR: To evaluate the use of local anaesthesia in 5‐aminolaevulinic acid (ALA) photodynamic therapy for superficial transitional cell carcinoma (TCC) of the bladder, and to provide further toxicity and tolerability data on this new method within the context of a phase 1 trial.
52
DNA Damage and Repair in Gorlin Syndrome and Normal Fibroblasts After Aminolevulinic Acid Photodynamic Therapy: A Comet Assay Study ¶
TL;DR: Using normal, untransformed, human fibroblasts, the effectiveness of aminolevulinic (ALA)-mediated photodynamic therapy (PDT) was investigated in terms of both clonogenic survival and DNA damage.
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Non-invasive pulsed ultrasound quantification of the resolution of basal cell carcinomas after photodynamic therapy.
TL;DR: Non-invasive pulsed ultrasound indicates that rates of resolution vary widely between BCC of similar initial thickness and that the probability of clearance of BCC by PDT is determined largely by the deepest, sometimes small, regions within a lesion, with the overall area being relatively unimportant.
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