James Mansfield
17 Papers
2 Citations
James Mansfield is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
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Papers
Extraterritorial Application and Customary Norm Assessment of Non-Refoulement: The Legality of Australia's 'Turn-Back' Policy
James Mansfield
- 31 Dec 2015
TL;DR: In this paper, the Commonwealth Government's border protection policy of turning back asylum seeker boats breaches its international obligation not to refoule refugees, as imposed under the Refugee Convention art 33(1).
85 Mapping the tumor microenvironment with sequential immunofluorescence, an automated image analysis pipeline, and spatial metrics
Joanna Kowal,Diego Gabriel Dupouy,P. M. Almeida,James Mansfield,Benjamin Pelz,Fabian Schneider,David Mason +6 more
- 01 Nov 2022
TL;DR: In this paper , the authors used the COMET platform and Oncotopix Discovery Software from Visiopharm to extract information from a single cell phenotypic information and biodistribution for tumor microenvironment (TME) studies.
Abstract 1709: Improved understanding of the biology and pathophysiology of the tumor microenvironment in PDAC samples revealed by InSituPlex, Imaging Mass Cytometry, and advanced image processing
Andrew A. Quong,Jordan Nieto,Derek Quong,Amanda Esch,Kirsteen H. Maclean,Mark Rees,Devan Fleury,Gourab Chatterjee,Keith Wharton,Jeppe Thagaard,Fabian Schneider,Dan Winkowski,James Mansfield +12 more
TL;DR: A unique tissue phenotyping workflow combining complementary methods that can unravel the complexity of the tumor microenvironment is demonstrated, highlighting how a workflow combining multiple elements provides utility, robustness, and an ability to derive biological insights in PDAC samples.
60 Enablement of single-cell spatial insight addressing T-cell and CAF involvement in pancreatic invasive ductal adenocarcinoma using AI-based deep learning image analysis
Andrew A. Quong,Smriti Kala,Nina Lane,Michelle MacPherson,Gourab Chatterjee,Devan Fleury,Kirsteen H. Maclean,Dan Winkowski,F. Schneider,Jeppe Thagaard,James Mansfield +10 more
- 01 Nov 2022
TL;DR: In this article , the authors demonstrate a spatial phenotyping workflow combining complementary methods that can unravel the complexity of the PDAC TME, in particular the important spatial relationships of different T cells subsets and CAFs.
143 A comprehensive workflow for highplex imaging, tissue segmentation, and multiplex cellular phenotyping for tumor microenvironment analysis
F. Schneider,Rasmus Ahrenkiel Lyngby,Rasmus Sorensen,Andrew A. Quong,Smriti Kala,Sam Lim,Clinton Hupple,Nina Lane,Michelle MacPherson,Jeppe Thagaard,Johan Dore-Hansen,James Mansfield +11 more
- 01 Nov 2022
TL;DR: In this article , the authors present a comprehensive workflow in the Oncotopix ® Discovery platform designed specifically for high-plex imaging analysis, covering tissue segmentation, cell segmentation based on IMC DNA images, cellular phenotyping, and spatial analyses.