James M. Kramer
Northwestern University
28 Papers
429 Citations
James M. Kramer is an academic researcher from Northwestern University. The author has contributed to research in topics: Caenorhabditis elegans & Mutant. The author has an hindex of 23, co-authored 28 publications. Previous affiliations of James M. Kramer include Howard Hughes Medical Institute & University of California, Los Angeles.
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Papers
Negative regulation of the heat shock transcriptional response by HSBP1
TL;DR: The homologous Caenorhabditis elegans protein was overexpressed in body wall muscle cells and was shown to block activation of the heat shock response from a heat shock promoter-reporter construct, consistent with a role for HSBP1 as a negative regulator of theHeat shock response.
Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases.
Irina Kramerova,Nobuko Kawaguchi,Liselotte I. Fessler,R.E. Nelson,Yali Chen,Andrei A. Kramerov,Marion Kusche-Gullberg,James M. Kramer,Brian D. Ackley,Aleksander Sieroń,Darwin J. Prockop,John H. Fessler +11 more
TL;DR: It is suggested that papilin influences cell rearrangements and may modulate metalloproteinases during organogenesis.
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Characterization of α1(IV) Collagen Mutations in Caenorhabditis elegans and the Effects of α1 and α2(IV) Mutations on Type IV Collagen Distribution
TL;DR: 11 mutations in emb-9, the α1(IV) collagen gene of Caenorhabditis elegans, are characterized that result in a spectrum of phenotypes and suggest that the nature of dominant interference caused by mutations in type IV collagen is different than that caused by mutation in fibrillar collagens.
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The basement membrane components nidogen and type XVIII collagen regulate organization of neuromuscular junctions in Caenorhabditis elegans.
Brian D. Ackley,Seong Hoon Kang,Jennifer R. Crew,Chris Suh,Yishi Jin,Yishi Jin,James M. Kramer +6 more
TL;DR: The results provide the first demonstration that basement membrane molecules are important for NMJ formation and/or maintenance in C. elegans and that collagen XVIII and nidogen can have important roles in synapse organization.
124
Structures and functions of collagens in Caenorhabditis elegans.
TL;DR: Two types of collagens have been identified in Caenorhabditis elegans corresponding to two types of extracellular matrix, the cuticle and basement membranes, indicating that normal basement membranes are required for embryogenesis and adult fertility.
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