James Harrison

TL;DR: The microbial chemistry of this unique heteropolysacchride is explored, the molecular genetics that underpins its fabrication are examined, and how the essential biosynthetic process might be exploited for the development of future anti-TB chemotherapies are discussed.

TL;DR: The constituents of honey are outlined and how they affect antibiotic potential in a clinical setting to facilitate the development of an optimally antimicrobial honey by either synthetic or semisynthetic production methods.

TL;DR: How it came to understand the pathogen, how it is currently treated and drug resistance mechanisms and novel treatments currently in development are discussed and improved in vivo methods of efficacy testing are examined.

TL;DR: Increasing the susceptibility of the organism to amoxicillin, by repurposing the β-lactamase inhibitor, relebactam, in combination with the front line M. abscessus drug imipenem, and establishing by multiple in vitro methods that this combination works synergistically to inhibit M.Abscessus.