James Hall
4 Papers
79 Citations
James Hall is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 3 publications.
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Papers
Effective drug combinations in breast, colon and pancreatic cancer cells
Patricia Jaaks,Elizabeth A. Coker,Daniel J. Vis,Olivia Edwards,Emma F. Carpenter,Simonetta Maria Leto,Lisa Dwane,Francesco Sassi,Howard Lightfoot,Syd Barthorpe,Dieudonne van der Meer,Wanjuan Yang,Alexandra Beck,Tatiana Mironenko,Caitlin Hall,James Hall,Iman Mali,Laura Richardson,Charlotte Tolley,James Morris,Frances Thomas,Ermira Lleshi,Nanne Aben,Cyril H. Benes,Andrea Bertotti,Livio Trusolino,Lodewyk F. A. Wessels,Mathew J. Garnett +27 more
TL;DR: In this paper , the potency and efficacy of 2,025 clinically relevant two-drug combinations were evaluated, generating a dataset encompassing 125 molecularly characterized breast, colorectal and pancreatic cancer cell lines.
Effective drug combinations in breast, colon and pancreatic cancer cells
Patricia Jaaks,Elizabeth A. Coker,Daniel J. Vis,Olivia Edwards,Emma F. Carpenter,Simonetta Maria Leto,Lisa Dwane,Francesco Sassi,Howard Lightfoot,Syd Barthorpe,Dieudonne van der Meer,Wanjuan Yang,Alexandra Beck,Tatiana Mironenko,Caitlin Hall,James Hall,Iman Mali,Laura Richardson,Charlotte Tolley,J. Morris,Frances Thomas,Ermira Lleshi,Nanne Aben,Cyril H. Benes,Andrea Bertotti,Livio Trusolino,Lodewyk F. A. Wessels,Mathew J. Garnett +27 more
TL;DR: In this paper , the potency and efficacy of 2,025 clinically relevant two-drug combinations were evaluated, generating a dataset encompassing 125 molecularly characterized breast, colorectal and pancreatic cancer cell lines.
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations.
A. Bashi,Elizabeth A. Coker,Krishna C. Bulusu,Patricia Jaaks,Claire Crafter,Howard Lightfoot,Marta Milo,Katrina McCarten,David F Jenkins,Dieudonne van der Meer,James T Lynch,Syd Barthorpe,Courtney L Andersen,Simon T Barry,Alexandra Beck,Justin Cidado,Jacob A Gordon,Caitlin Hall,James Hall,Iman Mali,Tatiana Mironenko,Kevin Mongeon,J. Morris,Laura Richardson,Paul Smith,Omid Tavana,Charlotte Tolley,Frances Thomas,Brandon S Willis,Wanjuan Yang,Mark J O'Connor,Ultan McDermott,Susan E. Critchlow,Lisa Drew,Stephen Fawell,Jerome T. Mettetal,Mathew J Garnett +36 more
TL;DR: Large-scale pan-cancer cell line screening identifies actionable and effective drug combinations.
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Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
Kunzah Jamal,Alessandro Galbiati,Joshua Armenia,Giuditta Illuzzi,James Hall,Sabrina Bentouati,Daniel Barrell,Miika Ahdesmäki,Mark J. O'Connor,Elisabetta Leo,Josep V. Forment +10 more
TL;DR: Investigations uncover XRCC3 gene silencing as a potential new prognostic biomarker of PARPi sensitivity in prostate cancer as well as unveiling loss of the DNA repair gene XR CC3 as a possible biomarkers of PARP inhibitor sensitivity in Prostate cancer.