James E. Tate
Brigham and Women's Hospital
14 Papers
308 Citations
James E. Tate is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Cervical intraepithelial neoplasia & Papillomaviridae. The author has an hindex of 12, co-authored 14 publications. Previous affiliations of James E. Tate include University of Michigan & Boston Children's Hospital.
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Papers
Vulvar intraepithelial neoplasia: age, morphological phenotype, papillomavirus DNA, and coexisting invasive carcinoma.
Hope K. Haefner,Hope K. Haefner,James E. Tate,James E. Tate,Catherine M. McLachlin,Catherine M. McLachlin,Christopher P. Crum,Christopher P. Crum +7 more
TL;DR: Three of six lesions of lichen sclerosus-associated VIN, including one involving invasive carcinoma in elderly women, contained HPV nucleic acids; all three lesions exhibited the features of classic VIN.
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Pathobiology of vulvar squamous neoplasia.
TL;DR: The pathway to both human papillomavirus positive and negative vulvar cancers may involve not only obvious precancerous changes but also biological events in the vulvar mucosa that precede the onset of morphological atypia.
78
Viral and histopathologic correlates of MN and MIB-1 expression in cervical intraepithelial neoplasia
Murray B. Resnick,Susan C. Lester,James E. Tate,Ellen E. Sheets,Candace K. Sparks,Christopher P. Crum +5 more
TL;DR: Although MN expression previously has been associated strongly with squamous carcinoma, it did not emerge as a specific marker for either cancer-associated HPV types or high grade CIN, emphasizing the interrelationship between vegetative viral functions (including viral replication) and morphological phenotype, irrespective of HPV type.
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•Journal Article
Prevalence of human papillomaviruses (HPV) in benign and malignant tumors of the upper respiratory tract.
TL;DR: The results suggest that HPV plays a role in the development of both LP and NIP, and that similar viral types (i.e., HPV6 and HPV11) may exhibit relative differences in their tissue specificity.
53
•Journal Article
Monoclonal origin of vulvar intraepithelial neoplasia and some vulvar hyperplasias.
TL;DR: The finding of monoclonal hyperplasia and lichen sclerosis suggests that clonal expansion may evolve before the development of morphological atypia in these epithelia.
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