James E. Messamore
Pfizer
5 Papers
83 Citations
James E. Messamore is an academic researcher from Pfizer. The author has contributed to research in topics: Antibody microarray & Immunology. The author has an hindex of 3, co-authored 3 publications.
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Papers
Comparison of antibody array substrates and the use of glycerol to normalize spot morphology.
Eric W Olle,James E. Messamore,Michael P. Deogracias,Shannon D. McClintock,Timothy Anderson,Kent J. Johnson +5 more
TL;DR: The studies found that epoxy-silane enhanced surface (ES) slides gave the greatest degree of binding along with a minimal background, however, larger antibody microarrays showed variability in spot size, high intra-spot coefficient of variation and drying artifacts.
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Screening of serum samples from Wegener's granulomatosis patients using antibody microarrays.
Eric W. Olle,Eric W. Olle,Michael P. Deogracias,James E. Messamore,Shannon D. McClintock,Adam G. Barron,Timothy Anderson,Kent J. Johnson +7 more
TL;DR: An antibody array was developed to help identify protein expression patterns in serum from patients with Wegener's Granulomatosis as compared to normals and several statistically significant increases were seen in the expression of angiotensin converting enzyme‐I, IFN‐γ, IL‐8, s‐ICAM‐1 and s‐VCAM in WG patients asCompared to controls.
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Laboratory safety evaluation of lokivetmab, a canine anti-interleukin-31 monoclonal antibody, in dogs.
M.J Krautmann,Rodney R. Walters,Vickie L. King,Kevin J. Esch,Sean P. Mahabir,A. J. Gonzales,Paul Joseph Dominowski,Laurel Sly,Duncan Mwangi,Dennis L. Foss,Sharath K. Rai,James E. Messamore,Genevieve Gagnon,Adam Schoell,Steve Dunham,Olivier M. Martinon +15 more
TL;DR: In this paper , the safety of Lokivetmab was evaluated in 2 studies by adapting the science-based, case-by-case approach used for preclinical and early clinical safety evaluation of human biopharmaceuticals.
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Lack of Interference of Oclacitinib with the results of intradermal testing or allergen-specific IgE serology in Dermatophagoides farinae-sensitized beagle dogs.
Michelle Aleo,James E. Messamore,Betsy A Nieto,Timothy J. Fleck,William R. Humphrey,Eileen M. Coscarelli,Sean P. Mahabir,Robert B. McCall,A. J. Gonzales +8 more
TL;DR: In this paper , the effects of oclacitinib on IDT and allergen-specific IgE serology testing using a laboratory model of house-dust mite sensitized Beagle dogs were determined.
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Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis.
Gonzales Andrea,William R. Humphrey,James E. Messamore,Timothy J. Fleck,Gregory J. Fici,John A. Shelly,Janet F. Teel,Gary F. Bammert,Dunham Steven A,Troy E. Fuller,Robert B. McCall +10 more
TL;DR: Canine IL-31 was detected in the majority of dogs with naturally occurring AD, suggesting that this cytokine may play an important role in pruritic allergic skin conditions, such as atopic dermatitis, in this species.