James D. Stewart
University of North Carolina at Chapel Hill
38 Papers
158 Citations
James D. Stewart is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Medicine & DNA methylation. The author has an hindex of 19, co-authored 38 publications.
Chat about Author
Papers
Epigenetically mediated electrocardiographic manifestations of sub-chronic exposures to ambient particulate matter air pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study.
Rahul Gondalia,Antoine R Baldassari,Katelyn M. Holliday,Anne E. Justice,James D. Stewart,Duanping Liao,Jeff D. Yanosky,Stephanie M. Engel,David S. Sheps,Kristina M. Jordahl,Parveen Bhatti,Steve Horvath,Themistocles L. Assimes,Ellen W. Demerath,Weihua Guan,Myriam Fornage,Jan Bressler,Kari E. North,Karen N. Conneely,Yun Li,Lifang Hou,Andrea A. Baccarelli,Eric A. Whitsel +22 more
TL;DR: In this article, the authors found that among racially/ethnically and environmentally diverse U.S. populations, sub-chronic exposures to coarser particulates may not exert appreciable, epigenetically mediated effects on cardiac autonomic function or ventricular repolarization.
6
Large-scale genome-wide pharmacogenetic meta-analysis of blood pressure response to antihypertensive drugs
Helen R. Warren,F.G. Sun,James D. Stewart,L. Broer,S. Trompet,H. Clarke,C. Sitlani,R. Noordam,J. Yao,L. Lange,T.S. Ahluwalia,Bruce M. Psaty,P Munroe,CHARGE-Pharmacogenomics Pgx +13 more
TL;DR: National Institutes for Health Research (NIHR), portfolio of translational research of the NIHR Biomedical Research Centre at Barts.
•Journal Article
Abstract 9793: Pcsk9 Loss-of-function Variants, Low-density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From the REGARDS Study and CHARGE Consortium
Shia T. Kent,Robert S. Rosenson,Christy L. Avery,Adolfo Correa,Steven R. Cummings,Adrienne Cupples,Mary Cushman,Daniel S. Evans,Vilmundur Gudnason,Tamara B. Harris,George Howard,Marguerite R. Irvin,Suzanne E. Judd,Joop Jukema,Leslie A. Lange,Emily B. Levitan,Xiaohui Li,Yongmei Liu,Iris Postmus,Bruce M. Psaty,Jerome I. Rotter,Monika M. Safford,Colleen M. Sitlani,Albert V. Smith,James D. Stewart,Stella Trompet,Fangui Sun,Ramachandran S. Vasan,J M Woolley,Eric A. Whitsel,Keri L Wiggins,James G. Wilson,Paul Muntner +32 more
TL;DR: Evidence is provided that PCSK9 variants are associated with lifelong reduction in LDL-C and may lead to lower CHD risk, but no effect on stroke risk.
1
Methylome-Wide Association Study of Central Adiposity Implicate Genes Involved in Immune and Endocrine Systems
Anne E. Justice,Geetha Chittoor,Rahul Gondalia,Phillip E. Melton,Phillip E. Melton,Elise Lim,Megan L. Grove,Eric A. Whitsel,Ching-Ti Liu,L. Adrienne Cupples,Lindsay Fernández-Rhodes,Lindsay Fernández-Rhodes,Weihua Guan,Jan Bressler,Myriam Fornage,Eric Boerwinkle,Eric Boerwinkle,Yun Li,Ellen W. Demerath,Nancy L. Heard-Costa,Daniel Levy,Daniel Levy,James D. Stewart,Andrea A. Baccarelli,Lifang Hou,Karen N. Conneely,Trevor A. Mori,Lawrence J. Beilin,Rae-Chi Huang,Penny Gordon-Larsen,Annie Green Howard,Kari E. North +31 more
TL;DR: Eleven CpGs were identified that were robustly associated with one or more central adiposity trait in adults and 2 in adolescents, including CpG site associations near TXNIP, ADCY7, SREBF1, and RAP1GAP2 that had not previously been associated with obesity-related traits.
Air pollution-associated changes in biomarkers of diabetes risk.
Katelyn M. Holliday,Archana P. Lamichhane,Rahul Gondalia,James D. Stewart,Jaime Madrigano,Regina A. Shih,Jeff D. Yanosky,Duanping Liao,Gregory A. Wellenius,Eric A. Whitsel +9 more
- 13 Aug 2019
TL;DR: This research presents a novel probabilistic approach that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals.