James B. Mitchell
5 Papers
James B. Mitchell is an academic researcher. The author has contributed to research in topics: Stromal cell & Adipose tissue. The author has an hindex of 5, co-authored 5 publications.
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Papers
Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers.
James B. Mitchell,Kevin R. Mcintosh,Sanjin Zvonic,Sara M. Garrett,Z. Elizabeth Floyd,Amy Kloster,Yuan Di C. Halvorsen,Robert W. Storms,Brian C. Goh,Gail Kilroy,Xiying Wu,Jeffrey M. Gimble,Jeffrey M. Gimble +12 more
TL;DR: The adherence to plastic and subsequent expansion of human adipose‐derived cells in fetal bovine serum‐supplemented medium selects for a relatively homogeneous cell population, enriching for cells expressing a stromal immunophenotype, compared with the heterogeneity of the crude SVF.
1.2K
Characterization and functionality of proliferative human Sertoli cells.
Kitty Chui,Alpa Trivedi,C. Yan Cheng,Diana B. Cherbavaz,Paul Dazin,Ai Lam Thu Huynh,James B. Mitchell,Gabriel A. Rabinovich,Linda J. Noble-Haeusslein,Constance M. John +9 more
TL;DR: The results show that functional human Sertoli cells can be propagated in vitro from testicular cells isolated from adult testis and should have important applications in studying infertility, reproductive toxicology, testicular cancer, and spermatogenesis.
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Allogeneic bone marrow stromal cells promote glial–axonal remodeling without immunologic sensitization after stroke in rats
Yi Li,Kevin R. Mcintosh,Jieli Chen,Chunling Zhang,Qi Gao,Jade Borneman,Kim Raginski,James B. Mitchell,Lihong Shen,Jing Zhang,Dunyue Lu,Michael Chopp +11 more
TL;DR: Allogeneic and syngeneic bone marrow stromal cell treatment after stroke in rats improved neurological recovery and enhanced reactive oligodendrocyte and astrocytes related axonal remodeling with no indication of immunologic sensitization in adult rat brain.
105
The immunogenicity of human adipose-derived cells: temporal changes in vitro.
Kevin R. Mcintosh,Sanjin Zvonic,Sara M. Garrett,James B. Mitchell,Z. Elizabeth Floyd,Lora Hammill,Amy Kloster,Yuan Di C. Halvorsen,Jenny P.-Y. Ting,Robert W. Storms,Brian C. Goh,Gail Kilroy,Xiying Wu,Jeffrey M. Gimble,Jeffrey M. Gimble,Jeffrey M. Gimble +15 more
TL;DR: The results support the feasibility of allogeneic human ASC transplantation and show that adherence to plastic and subsequent expansion of human adipose‐derived cells selects for a relatively homogeneous cell population based on immunophenotype.
Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice.
Jing Zhang,Yi Li,Jieli Chen,Yisheng Cui,Mei Lu,Stanton B. Elias,James B. Mitchell,Lora Hammill,Padmavathy Vanguri,Michael Chopp,Michael Chopp +10 more
TL;DR: Data indicate that hBMSC treatment improved functional recovery after EAE in mice, possibly, via reducing inflammatory infiltrates and demyelination areas, stimulating oligodendrogenesis, and by elevating BDNF expression.