Jake B. Bailey
University of California, San Diego
20 Papers
47 Citations
Jake B. Bailey is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Chemistry & Catalysis. The author has an hindex of 10, co-authored 15 publications. Previous affiliations of Jake B. Bailey include Northern Arizona University.
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Papers
Halogen interactions in protein-ligand complexes: implications of halogen bonding for rational drug design.
TL;DR: Halogen bonding interactions between halogenated ligands and proteins were examined using the crystal structures deposited to date in the PDB and it is revealed that while fluorine and chlorine have strong tendencies favoring interactions with the backbone Lewis bases at glycine, the trend is not restricted to the achiral amino acid backbone for larger halogens.
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Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks.
TL;DR: The integration of macromolecular ferritin protein crystals with integrated hydrogel polymers gives a composite material that expands isotropically and reversibly to twice its size while maintaining periodicity, resists fragmentation and self-heals efficiently.
Constructing protein polyhedra via orthogonal chemical interactions.
Eyal Golub,Rohit H. Subramanian,Julian Esselborn,Robert G. Alberstein,Jake B. Bailey,Jerika A. Chiong,Xiaodong Yan,Timothy Booth,Timothy S. Baker,F. Akif Tezcan +9 more
TL;DR: This work shows that a monomeric protein (protomer) appropriately modified with biologically inspired hydroxamate groups and zinc-binding motifs assembles through concurrent Fe 3+ and Zn 2+ coordination into discrete dodecameric and hexameric cages.
An Exceptionally Stable Metal-Organic Framework Constructed from Chelate-Based Metal-Organic Polyhedra.
Jerika A. Chiong,Jie Zhu,Jake B. Bailey,Mark Kalaj,Rohit H. Subramanian,Wenqian Xu,Seth M. Cohen,F. Akif Tezcan +7 more
TL;DR: Fe-HAF-1 presents a new addition to a small group of chelate-based MOFs and provides a rare framework whose 3D connectivity is exclusively formed by metal-hydroxamate coordination, resulting in efficient separation of organic dyes and other charged species in a size-selective fashion.
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Metal-Directed Design of Supramolecular Protein Assemblies.
TL;DR: Two design strategies are developed, metal-directed protein self-assembly (MDPSA) and metal-templated interface redesign (MeTIR), inspired by both the proposed evolutionary roles of metals and their prevalence in natural PPIs.