Jacquelyn Shaw
Columbia University
24 Papers
Jacquelyn Shaw is an academic researcher from Columbia University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 3, co-authored 5 publications. Previous affiliations of Jacquelyn Shaw include Albert Einstein College of Medicine & Columbia University Medical Center.
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Papers
A secreted PTEN phosphatase that enters cells to alter signaling and survival.
Benjamin D. Hopkins,Barry Fine,Nicole Steinbach,Nicole Steinbach,Meaghan Dendy,Zachary Rapp,Jacquelyn Shaw,Jacquelyn Shaw,Kyrie Pappas,Kyrie Pappas,Jennifer S. Yu,Cindy Hodakoski,Sarah M. Mense,Joshua U. Klein,Joshua U. Klein,Sarah Pegno,Maria Luisa Sulis,Maria Luisa Sulis,Hannah E. Goldstein,Hannah E. Goldstein,Benjamin Amendolara,Benjamin Amendolara,Liang Lei,Liang Lei,Matthew Maurer,Matthew Maurer,Jeffrey N. Bruce,Peter Canoll,Peter Canoll,Hanina Hibshoosh,Hanina Hibshoosh,Ramon Parsons +31 more
TL;DR: A 576–amino acid translational variant of PTEN, termed PTEN-Long, that arises from an alternative translation start site 519 base pairs upstream of the ATG initiation sequence, adding 173 N-terminal amino acids to the normal PTEN open reading frame may have therapeutic uses.
Metformin and erlotinib synergize to inhibit basal breast cancer
Ying-Ka Ingar Lau,Xing Du,Vinayak Rayannavar,Benjamin D. Hopkins,Jacquelyn Shaw,Eliana Bessler,Tiffany Thomas,Maira M. Pires,Megan Keniry,Ramon Parsons,Serge Cremers,Matthias Szabolcs,Matthew A. Maurer +12 more
TL;DR: It is suggested that biguanides combined with EGFR inhibitors have the potential to outperform other targeted drug combinations and could be employed in other breast cancer subtypes, as well as other tumor types, with activated EGFR and PI3K signaling.
Lack of Effect of Coenzyme Q10 on Doxorubicin Cytotoxicity in Breast Cancer Cell Cultures
TL;DR: The clinical testing of CoQ10 as a supplement to prevent doxorubicin-induced cardiotoxicity requires confidence that it does not decrease the efficacy of chemotherapy, and this study demonstrated that intracellular and mitochondrial Co Q10 concentrations increased substantially as higher exogenous concentrations were administered to breast cancer cells.
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Fertility Preservation for Adolescent and Young Adult Transmen: A Case Series and Insights on Oocyte Cryopreservation
TL;DR: Oocyte cryopreservation is a safe fertility preservation option in AYA transmen and is an important aspect of providing comprehensive transgender care, as well as improving the education and comfort of patients and providers with fertility preservation.
Pausing the pill: taking a break from oral contraceptive pills (ocp) before fertility preservation (fp) does not impact the metaphase ii oocyte (m2) yield
Sarah D. Cascante,Koral Cohen,Brooke Wertz,Jacquelyn Shaw,Jennifer K. Blakemore +4 more
TL;DR: A "break" from oral contraceptive pills before fertility preservation does not impact metaphase II oocyte yield, and patients who used OCPs within 1 year of fertility preservation had equivalent M2 yields compared to non-OCP users.
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