J. Yang
Anhui Medical University
7 Papers
17 Citations
J. Yang is an academic researcher from Anhui Medical University. The author has contributed to research in topics: Age of onset & Genetic model. The author has an hindex of 5, co-authored 7 publications.
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Papers
The genetic epidemiology of alopecia areata in China
Sen Yang,J. Yang,Jiang-Bo Liu,Hua Wang,Q. Yang,Min Gao,Yan-Hua Liang,G.S. Lin,Da Lin,X.L. Hu,L. Fan,Xiaoguang Zhang +11 more
TL;DR: This data indicates that preoperatively diagnosed alopecia areata is an organ‐specific autoimmune disease with genetic predisposition and an environmental trigger and there are few clinical data in Asians.
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Sex-specific differences in the relationship between the single-nucleotide polymorphism rs2298804 of FCER1A and the susceptibility to systemic lupus erythematosus in a Chinese Han population.
TL;DR: A recent study identified the high‐affinity IgE receptor α‐chain (FcεRIα) gene FCER1A as a susceptibility locus influencing total serum IgE levels.
9
A novel missense mutation of the ATP2A2 gene in a Chinese family with Darier's disease.
Sen Yang,Liangdan Sun,Hong-Sheng Liu,Ji-Yun Wang,Ping-Ping He,Ming Li,Min Gao,Jiang-Bo Liu,J. Yang,Zaixing Wang,Yi-Yuan Zhu,Da Lin,Xuejun Zhang +12 more
TL;DR: A three-generation family with DD is reported, and a novel missense mutation A→G was identified in exon 12, nucleotide 1704, which leads to the substitution of lysine by arginine at codon 514 (K514R), which further illustrates the extensive diversity of mutational events that lead to the different phenotypes of DD.
5
A new glycine substitution mutation in the COL7A1 gene in a Chinese family with dominant dystrophic epidermolysis bullosa.
TL;DR: A Chinese family with a four‐generation pedigree of DDEB is identified, in whom a novel glycine substitution mutation in COL7A1 was demonstrated, which resulted in a glycine to arginine substitution in the triple‐helical domain of type VII collagen.
4
Characteristics of genetic epidemiology and genetic models for vitiligo.
Xuejun Zhang,Jiang-Bo Liu,Jin-Ping Gui,Ming Li,Quan-Geng Xiong,Hong-Bo Wu,Jin-Xian Li,Sen Yang,Hongyan Wang,Min Gao,J. Yang,Q. Yang +11 more
TL;DR: Different phenotypes of vitiligo had different pathogeneses and genetic backgrounds, indicating that onset of vitILigo is possibly affected by both genetic backgrounds and common environmental factors.