J. Tio
University of Münster
30 Papers
132 Citations
J. Tio is an academic researcher from University of Münster. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 10, co-authored 20 publications.
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Papers
Endothelin-1-, Endothelin-A-, and Endothelin-B-Receptor Expression Is Correlated with Vascular Endothelial Growth Factor Expression and Angiogenesis in Breast Cancer
Pia Wülfing,Christian Kersting,J. Tio,Rudolph-Josef Fischer,Christian Wülfing,Christopher Poremba,Raihanatou Diallo,Werner Böcker,Ludwig Kiesel +8 more
TL;DR: The results indicate that increased ET-1, ETAR, and ETBR expression is associated with increased VEGF expression and higher vascularity of breast carcinomas and, thus, could be involved in the regulation of angiogenesis in breast cancer.
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•Journal Article
Predictive value of syndecan-1 expression for the response to neoadjuvant chemotherapy of primary breast cancer.
Martin Götte,Christian Kersting,Maria Ruggiero,J. Tio,Augustinus H. Tulusan,Ludwig Kiesel,Pia Wülfing +6 more
TL;DR: Syndecan-1-expressing breast carcinomas show a trend towards a decreased response to chemotherapy, which is more frequent in ductal invasive carcinomas than in other histological types.
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Expression patterns of angiogenic and lymphangiogenic factors in ductal breast carcinoma in situ.
Pia Wülfing,Christian Kersting,Horst Buerger,B Mattsson,R Mesters,C Gustmann,B Hinrichs,J. Tio,Werner Böcker,Ludwig Kiesel +9 more
TL;DR: The findings of VEGF-C and its receptor Flt-4 as lymphangiogenic factors being expressed in tumour cells of nearly all DCIS lesions and the observed expression of various angiogenic growth factors in most DCIS suggest that in situ carcinomas are capable of inducing angiogenesis and lymphang iogenesis.
Detection of peritoneal endometriotic lesions by autofluorescence laparoscopy.
TL;DR: In this article, the authors evaluated the feasibility of autofluorescence laparoscopy in the diagnosis of endometriotic lesions and found that the combination of white light illumination and auto-fluorescence is significantly superior to white light ilumination alone in detecting nonpigmented endometria.
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Expression of endothelin-A-receptor predicts unfavourable response to neoadjuvant chemotherapy in locally advanced breast cancer.
Pia Wülfing,J. Tio,Christian Kersting,Barbara Sonntag,Horst Buerger,Christian Wülfing,U. Euler,Werner Boecker,A. H. Tulusan,Ludwig Kiesel +9 more
TL;DR: Data indicate that increased expression of ETAR in breast carcinomas is associated with resistance to chemotherapy, and determined ETAR status may serve as a predictive marker for identifying patients less likely to be responsive to conventional chemotherapy.
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