J. Rowe
7 Papers
1 Citations
J. Rowe is an academic researcher. The author has contributed to research in topics: Medicine & Progressive supranuclear palsy. The author has an hindex of 1, co-authored 1 publications.
Chat about Author
Papers
Hospitalisation for COVID-19 predicts long lasting cerebrovascular impairment: A prospective observational cohort study
Kamen A. Tsvetanov,Lennart R. B. Spindler,Emmanuel Stamatakis,Virginia F. J. Newcombe,Victoria Lupson,Doris A. Chatfield,Anne E. Manktelow,Joanne G. Outtrim,Anne Elmer,Nathalie Kingston,John S. Bradley,E.T. Bullmore,J. Rowe,David K. Menon,the Cambridge NeuroCOVID Group,the NIHR COVID-19 BioResource,the Cambridge NIHR Clinical Research Facility,The CITIID-NIHR BioResource COVID-19 Collaboration +17 more
TL;DR: The results indicate chronic cerebrovascular impairment following severe acute COVID-19, with the potential for long-term consequences on cognitive function and mental wellbeing.
10
Synaptic loss in behavioural variant frontotemporal dementia revealed by UCB-J PET
Maura Malpetti,P. Simon Jones,Thomas E. Cope,Negin Holland,Michelle Naessens,Matthew A Rouse,George Savulich,Tim D. Fryer,Yi Hong,Selena Milicevic Sephton,Franklin I. Aigbirhio,J. T. O'Brien,J. Rowe +12 more
TL;DR: There is widespread frontotemporal loss of synapses in symptomatic bvFTD, in proportion to disease severity, and [11C]UCB-J PET could support translational studies and experimental medicines strategies for new disease-modifying treatments for neurodegeneration.
Trajectories of neurodegeneration and seed amplification biomarkers prior to disease onset in individuals at risk of prion disease
Tze How Mok,Akin Nihat,Nour K. Majbour,Danielle Sequeira,Leah Holm-Mercer,Thomas Coysh,Lee Darwent,Matthew Batchelor,Bradley R. Groveman,Cd Orrù,A. Hughson,Amanda Heslegrave,R. Laban,E. Veleva,Ross W. Paterson,Ashvini Keshavan,Jon M. Schott,Imogen Swift,Carolin Heller,J. Rohrer,Alexander Gerhard,Christopher C Butler,J. Rowe,Mario Masellis,Miles D. Chapman,Margaret C. Lunn,Jan Bieschke,P. S. Jackson,Henrik Zetterberg,Byron Caughey,Peter Rudge,John Collinge,Simon Mead +32 more
TL;DR: In this article , the authors report the accrual of a longitudinal biofluid resource in patients, controls and healthy people at-risk of prion diseases, to which ultrasensitive techniques such as real-time quaking-induced conversion (RT-QuIC), and single molecule array (Simoa) digital immunoassays were applied for preclinical biomarker discovery.
1
Neurodevelopmental effects of genetic frontotemporal dementia mutations revealed by total intracranial volume differences
I. So,Arabella Bouzigues,L. Russell,P. Foster,E. Ferry-Bolder,John C. van Swieten,Lize C. Jiskoot,H. Seelaar,R. Sanchez-Valle,Robert Laforce,C. Graff,D. Galimberti,R. Vandenberghe,Alexandre de Mendonça,P. Tiraboschi,I. Santana,A. Gerhard,J. Levin,S. Sorbi,Markus Otto,F. Pasquier,S. Ducharme,Christopher C Butler,Isabelle Le Ber,C. Tartaglia,M. Masellis,J. Rowe,M. Synofzik,F. Moreno,B. Borroni,T. Kolander,C. Mester,Danielle Brushaber,K. Kantarci,H. W. Heuer,L. K. Forsberg,Johnathan D. Rohrer,B. Boeve,A. Boxer,H. Rosen,E. Finger,Frontotemporal Dementia Pr +41 more
TL;DR: This study investigates neurodevelopmental effects of genetic frontotemporal dementia mutations, revealing significant differences in total intracranial volume (TIV) and education between mutation carriers and non-carriers, with GRN and MAPT mutations linked to structural neurodevelopmental changes.