J.P. Brun
Medical University of Warsaw
25 Papers
144 Citations
J.P. Brun is an academic researcher from Medical University of Warsaw. The author has contributed to research in topics: Intensive care unit & Sepsis. The author has an hindex of 12, co-authored 25 publications.
Chat about Author
Papers
Procalcitonin, interleukin 6 and systemic inflammatory response syndrome (SIRS): early markers of postoperative sepsis after major surgery
TL;DR: PCT and IL-6 appear to be early markers of subsequent postoperative sepsis in patients undergoing major surgery for cancer, which could allow identification of postoperativeSepsis complications.
253
De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study
Djamel Mokart,Géraldine Slehofer,Jérôme Lambert,Antoine Sannini,Laurent Chow-Chine,J.P. Brun,Pierre Berger,Segolene Duran,Marion Faucher,J.-L. Blache,Colombe Saillard,Norbert Vey,Marc Leone +12 more
TL;DR: The data suggest that, in ICU, de-escalation of the empirical antimicrobial treatment is frequently applied in neutropenic cancer patients with severe sepsis, and no evidence of any prognostic impact of this de- escalation was found.
129
Prognosis of acute respiratory distress syndrome in neutropenic cancer patients
Djamel Mokart,Thomas van Craenenbroeck,Jérôme Lambert,Julien Textoris,J.P. Brun,Antoine Sannini,Laurent Chow-Chine,Smail Hamouda,Louis Fouché,Florence Ettori,Marion Faucher,J.-L. Blache +11 more
TL;DR: At ICU admission, first-line chemotherapy, lobar ARDS and antibiotic treatment active on difficult-to-treat bacteria were associated with survival, and during ICU stay, mortality was associated with organ dysfunctions and use of vasopressors.
63
N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock.
Djamel Mokart,Antoine Sannini,J.P. Brun,Marion Faucher,Didier Blaise,J.-L. Blache,Catherine Faucher +6 more
TL;DR: It is observed that critically ill cancer patients with septic shock have an approximately 50% chance of survival to ICU discharge and NT-proBNP could be a useful tool for detecting high-risk cancer patients within the first 24 hours after septicshock diagnosis.
Neutropenic cancer patients with severe sepsis: need for antibiotics in the first hour
Djamel Mokart,Colombe Saillard,Antoine Sannini,Laurent Chow-Chine,J.P. Brun,Marion Faucher,J.-L. Blache,Didier Blaise,Marc Leone +8 more
TL;DR: The findings suggest that, in the ICU, a 1-h delay between the antimicrobial treatment initiation and the first sign of sepsis was the strongest predictor of ICU mortality in neutropenic cancer patients.
41