J Mocco
Mount Sinai Hospital
8 Papers
115 Citations
J Mocco is an academic researcher from Mount Sinai Hospital. The author has contributed to research in topics: Randomized controlled trial & Stroke. The author has an hindex of 6, co-authored 8 publications.
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Papers
Endovascular therapy for acute ischemic stroke is indicated and evidence based: a position statement
J Mocco,David Fiorella,Kyle M Fargen,Felipe C. Albuquerque,Michael Chen,Rishi Gupta,Joshua A Hirsch,Italo Linfante,William J. Mack,Ansaar T Rai,Robert W Tarr +10 more
TL;DR: A critical and evidence based evaluation of the available data supports the superiority of IAT over standard medical therapies in patients presenting with AIS from LVO within 6 h of stroke onset and having a small infarct core and believes randomization of these patients in trials may no longer be ethical as general community equipoise appropriately disappears.
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Thrombectomy for acute ischemic stroke: an evidence-based treatment.
David Fiorella,Kyle M Fargen,J Mocco,Felipe C. Albuquerque,Joshua A Hirsch,Michael Chen,Rishi Gupta,Italo Linfante,William J. Mack,Ansaar T Rai,Robert W Tarr +10 more
TL;DR: The overarching message to the medical community and lay press was that these studies provided unambiguous evidence that mechanical thrombectomy was ineffective in treating acute stroke secondary to emergent large vessel occlusion (ELVO), but it was clear that these three trials had significant shortcomings.
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Neurothrombectomy trial results: stroke systems, not just devices, make the difference
J Mocco,Kyle M Fargen,Mayank Goyal,Elad I. Levy,Peter Mitchell,Bruce C.V. Campbell,Charles B. L. M. Majoie,Diederik W.J. Dippel,Pooja Khatri,Michael D. Hill,Jeffery L Saver +10 more
TL;DR: It is hoped that, through greater education initiatives, robust resource investment, and developing quality-based certification processes, the results demonstrated by these trials may be extrapolated to greater numbers of centers – in turn allowing greater access for patients to high-quality, advanced stroke care.
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Advanced Imaging of Intracranial Atherosclerosis: Lessons from Interventional Cardiology.
Davor Pavlin-Premrl,Rahul Sharma,Bruce C.V. Campbell,J Mocco,Nicholas L. Opie,Thomas J Oxley +5 more
TL;DR: Fractional flow reserve (FFR), intravascular ultrasound (IVUS), and optical coherence tomography (OCT), used to improve patient selection and stent placement in interventional cardiology, may be useful in avoiding perforator strokes, a common complication of stenting.
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A collaborative sequential meta-analysis of individual patient data from randomized trials of endovascular therapy and tPA vs. tPA alone for acute ischemic stroke: ThRombEctomy And tPA (TREAT) analysis: statistical analysis plan for a sequential meta-analysis performed within the VISTA-Endovascular collaboration.
Rachael L. MacIsaac,Pooja Khatri,Martin Bendszus,Serge Bracard,Joseph P. Broderick,Bruce C.V. Campbell,Alfonso Ciccone,Antoni Dávalos,Stephen M. Davis,Andrew M. Demchuk,Hans-Christoph Diener,Diederik W.J. Dippel,Geoffrey A. Donnan,Jens Fiehler,David Fiorella,Mayank Goyal,Werner Hacke,Michael D. Hill,Reza Jahan,Edward C. Jauch,Tudor G Jovin,Chelsea S. Kidwell,David S Liebeskind,Charles B. L. M. Majoie,Sheila Cristina Ouriques Martins,Peter Mitchell,J Mocco,Keith W. Muir,Keith W. Muir,Raul G. Nogueira,Jeffrey L. Saver,Wouter J. Schonewille,Adnan H. Siddiqui,Goetz Thomalla,Thomas A. Tomsick,Aquilla S Turk,Philip White,Osama O. Zaidat,Kennedy R. Lees +38 more
TL;DR: This collaborative meta-analysis of individual participant data from randomized trials of endovascular therapy vs. control in conjunction with intravenous thrombolysis will demonstrate the efficacy and generalizability of endOVascular therapy with intravenously thrombectomylysis as a concomitant medication.
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