J. Kovar
12 Papers
71 Citations
J. Kovar is an academic researcher. The author has contributed to research in topics: Cholesterol & Reverse cholesterol transport. The author has an hindex of 5, co-authored 12 publications.
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Papers
Plasma levels of remnant particles are determined in part by variation in the APOC3 gene insulin response element and the APOCI–APOE cluster
Dawn M. Waterworth,Jaroslav A. Hubacek,Jan Pitha,J. Kovar,Rudolf Poledne,Steve E. Humphries,P.J. Talmud +6 more
TL;DR: The relationship was investigated between remnant particle triglyceride/cholesterol concentrations and polymorphisms in the genes APOC3, APOE, APOCI, APOB, and APOB and it appeared that the APOE-CI effects on RLPC were independent of their effects on plasma cholesterol, but the effects of AP OC3 and APoe-CI on RLPTG could not be separated from their effect on plasma Tg levels.
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•Journal Article
The A-204C polymorphism in the cholesterol 7alpha-hydroxylase (CYP7A1) gene determines the cholesterolemia responsiveness to a high-fat diet
TL;DR: The polymorphism in the cholesterol 7alpha-hydroxylase promotor region seems to be involved in the determination of cholesterol and LDL-C responsiveness to a dietary fat challenge.
•Journal Article
The effect of an acute fat load on endothelial function after different dietary regimens in young healthy volunteers.
TL;DR: A single high-fat meal at the different dietary regimen did not significantly influence the vasoreactivity of the brachial artery in young volunteers.
Life style change and reverse cholesterol transport in obese women.
TL;DR: There was highly significant negative correlation between individual decrease of body weight and an increase of RCT, and substantial weight loss is necessary to increase RCT in obese women after 9-week intervention.
•Journal Article
The association between subclinical atherosclerosis in carotid arteries and Connexin 37 gene polymorphism (1019C>T; Pro319Ser) in women.
Jan Pitha,Jaroslav A. Hubacek,Renata Cifkova,Zdenka Škodová,Petr Stavek,Lánská,J. Kovar,Rudolf Poledne +7 more
TL;DR: In women with higher fasting glycemia TT genotype of Cx37 polymorphism was protective against subclinical atherosclerosis, therefore, the C x37 gene may exert completely different effects in the artery wall, depending on glyCEmia.
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