J. Kaftalli
4 Papers
J. Kaftalli is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has co-authored 3 publications.
Chat about Author
Papers
Next-Generation Sequencing of a Large Gene Panel for Outcome Prediction of Bariatric Surgery in Patients with Severe Obesity
Gabriele Bonetti,Kristjana Dhuli,Maria Rachele Ceccarini,J. Kaftalli,Michele Samaja,Vincenza Precone,S. Cecchin,Paolo Enrico Maltese,Giulia Guerri,Giuseppe Marceddu,Tommaso Beccari,Barbara Aquilanti,Valeria Velluti,Giuseppina Matera,M. Perrone,Amerigo Iaconelli,Francesca Colombo,Francesco Greco,Marco Raffaelli,Mahmut Cerkez Ergoren,Matteo Bertelli +20 more
TL;DR: In this paper , the authors developed an NGS gene panel, comprising 72 diagnostic genes and 244 candidate genes, and sequenced 247 adult obese Italian patients to predict the outcome of bariatric surgery.
Genetic Analysis of Patients with Congenital Hypogonadotropic Hypogonadism: A Case Series
Rossella Cannarella,Carmelo Gusmano,Rosita A. Condorelli,Andrea Bernini,J. Kaftalli,Paolo Enrico Maltese,Stefano Paolacci,Astrit Dautaj,Giuseppe Marceddu,Matteo Bertelli,Sandro La Vignera,Aldo E. Calogero +11 more
TL;DR: In this article , the results of a clinical and genetic investigation of five unrelated patients with cHH/Kallmann syndrome were analyzed using a customized gene panel, where patients were diagnosed according to the clinical, hormonal, and radiological criteria of the European Consensus Statement.
Towards a Long-Read Sequencing Approach for the Molecular Diagnosis of RPGRORF15 Genetic Variants
Gabriele Bonetti,William Cozza,A. Bernini,J. Kaftalli,Chiara Mareso,F. Cristofoli,Maria Chiara Medori,Leonardo Colombo,Salvatore Martella,G. Staurenghi,Anna P. Salvetti,Benedetto Falsini,Giorgio Placidi,Marcella Attanasio,Grazia Pertile,Mario Bengala,Francesca Bosello,Antonio Petracca,Fabiana D'Esposito,B. Toschi,Paolo Lanzetta,Federico Ricci,F. Viola,Giuseppe Marceddu,Matteo Bertelli +24 more
TL;DR: The results showed that NGS has a low coverage of the ORF15 region, while PacBio was able to sequence the region of interest and detect eight genetic variants, of which four are likely pathogenic, and provide a way to predict their pathogenicity.
2
Polymorphisms, diet and nutrigenomics
Aysha Karim Kiani,Gabriele Bonetti,Kevin Donato,J. Kaftalli,Karen L. Herbst,Liborio Stuppia,F. Fioretti,Savina Nodari,Marco Alfonso Perrone,Pietro Chiurazzi,Francesco Bellinato,Paolo Gisondi,Matteo Bertelli +12 more
TL;DR: In this paper , the authors proposed the use of nutrigenomics to improve and optimize a healthy, balanced diet in clinical settings could be an effective approach for long-term lifestyle changes that might lead to consistent weight loss and improve quality of life.