J. John
Lund University
9 Papers
304 Citations
J. John is an academic researcher from Lund University. The author has contributed to research in topics: Tidal volume & Pulmonary alveolus. The author has an hindex of 8, co-authored 9 publications.
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Papers
Surfactant dysfunction makes lungs vulnerable to repetitive collapse and reexpansion.
TL;DR: It is concluded that perturbation of the surfactant system makes lungs vulnerable to injury by RECOREX, and the combination of DOSS and NEEP might lead to leakage of plasma proteins into alveoli, causing inactivation of surfactants and increased shear forces with resulting lung damage.
221
Additive nature of distension and surfactant perturbation on alveolocapillary permeability
TL;DR: The diverse kinetics of clearance during large tidal volume ventilation and surfactant dysfunction suggest the presence of different mechanisms affecting the barrier, which superimpose to produce lung injury.
25
Respiratory mechanics in rabbits ventilated with different tidal volumes
TL;DR: Both static and viscoelastic behaviours were linear up to larger volume ranges at large VT compared to moderate VT and Compliance increased with VT.
22
Biexponential pulmonary clearance of 99mTc-DTPA induced by detergent aerosol
TL;DR: It is concluded that detergent induces a biexponential clearance of 99mTc-DTPA by accelerating the transfer of tracer across the alveolocapillary barrier in a proportion of lung units in a dose-related manner.
21
Dynamic properties of body plethysmographs and effects on physiological parameters.
TL;DR: The effect of distortion of flow signals from 13 infants in whom flow and esophageal pressure had been recorded was studied, finding a volume-displacement plethysmograph with moderately high resistance of the flowmeter, corrected for internal pressure and inertia gives the best possible results.
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