J.E. Parker
University of Cambridge
9 Papers
133 Citations
J.E. Parker is an academic researcher from University of Cambridge. The author has contributed to research in topics: Fludarabine & Myelodysplastic syndromes. The author has an hindex of 6, co-authored 9 publications.
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Papers
‘Low‐risk’ myelodysplastic syndrome is associated with excessive apoptosis and an increased ratio of pro‐ versus anti‐apoptotic bcl‐2‐related proteins
TL;DR: It is confirmed that CD34+ cell apoptosis was significantly increased in MDS subtypes RA and RARS and fell with disease progression and no correlation between pro‐ v anti‐apoptotic Bcl‐2‐family‐protein ratios and the degree of apoptosiswas observed.
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Allogeneic stem-cell transplantation for lymphoproliferative disorders using BEAM–CAMPATH (± fludarabine) conditioning combined with post-transplant donor-lymphocyte infusion
R.J. Lush,A P Haynes,Jennifer Byrne,G Cull,G. I. Carter,A Pagliuca,J.E. Parker,Ghulam J. Mufti,P Mahendra,Charles Craddock,J. A. Liu Yin,Mamta Garg,H. G. Prentice,Michael N. Potter,Nigel H. Russell +14 more
TL;DR: Encouraging results show that this reduced-intensity conditioning regimen is effective, with a low-toxicity profile compared with conventional TBI-based conditioning, and certainly merits further evaluation in this setting.
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Discrepancy between phenotype and genotype on screening for factor V Leiden after transplantation
J.E. Parker,Antonio Pagliuca,Taya Kitiyakara,Malcolm Whitehead,Nigel Heaton,John O'Grady,Roopen Arya +6 more
TL;DR: Factor V (FV) Leiden is the most common genetic defect found in persons of European descent with venous thromboembolism and the 1691G>A transition determines the R506Q substitution.
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Chronic myelomonocytic leukaemia (CMML) presenting as a thyroid mass
TL;DR: An 87-year-old woman was referred to the endocrine surgical outpatient clinic with a 6-month history of an enlarging neck mass associated with dysphagia and died 1 month after presentation from overwhelming sepsis.
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