J. E. Brown
University of Bradford
4 Papers
63 Citations
J. E. Brown is an academic researcher from University of Bradford. The author has contributed to research in topics: High-performance liquid chromatography & Reversed-phase chromatography. The author has an hindex of 3, co-authored 4 publications.
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Papers
Solid-phase extraction and optimized separation of doxorubicin, epirubicin and their metabolites using reversed-phase high-performance liquid chromatography.
TL;DR: A reversed-phase isocratic high-performance liquid chromatographic method is described in which a formal structured procedure was applied to predict the mobile phase composition giving optimal baseline resolution of the clinically important anticancer agents doxorubicin and 4'-epidoxorubICin (epirubic in) and their principal metabolites, and daunorubsicin (internal standard).
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Optimised separation of E- and Z- isomers of tamoxifen, and its principal metabolites using reversed-phase high performance liquid chromatography.
J. E. Manns,S. Hanks,J. E. Brown +2 more
TL;DR: A reversed phase isocratic high-performance liquid chromatographic method is reported in which a formal structured procedure was applied to predict the mobile phase composition giving baseline resolution of the clinically important triphenylethylene antioestrogenic agent (Z)-tamoxifen, its principal (Z)metabolites, and also the clinically relevant (E)-geometric isomers of tamoxifens and 4-hydroxytamxifen.
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Novel instrumentation and biomedical applications of very near-infrared fluorescence
Marc B. Brown,James N. Miller,D. P. Riley,Nichola J. Seare,Martin J. Bloxham,Steve J. Hill,Paul J. Worsfold,J. E. Manns,S. Hanks,J. E. Brown,J. A. Double +10 more
TL;DR: A high wavelength fluorescent probe was added to four proteins, viz., bovine albumin, alpha 1-acid glycoprotein, beta-lactoglobulin and ovomucoid, showing that the binding site is less electrostatic and more hydrophobic in nature.
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