J Döscher
University of Ulm
37 Papers
21 Citations
J Döscher is an academic researcher from University of Ulm. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 13 publications.
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Papers
NF-κB and Its Role in Checkpoint Control.
Annika C Betzler,Marie-Nicole Theodoraki,Patrick J. Schuler,J Döscher,Simon Laban,Thomas K. Hoffmann,Cornelia Brunner +6 more
TL;DR: This review discusses recent evidence for an association of NF-κB and immune checkpoint expression and examines the therapeutic potential of inhibitors targeting either NF-σB directly or molecules involved in NF-β regulation in combination with immune checkpoint blockade.
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Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer.
Katrin Schmitt,Britta Molfenter,Natalia Koerich Laureano,Natalia Koerich Laureano,Natalia Koerich Laureano,Bouchra Tawk,Matthias Bieg,Xavier Pastor Hostench,Dieter Weichenhan,Nina D. Ullrich,Viny Shang,Daniela Richter,Fabian Stögbauer,Lea Schroeder,Bianca De Bem Prunes,Fernanda Visioli,Pantelis Varvaki Rados,Adriana Jou,Adriana Jou,Michaela Plath,P.A. Federspil,Julia Thierauf,J Döscher,Stephanie E. Weissinger,Thomas K. Hoffmann,Steffen Wagner,Claus Wittekindt,Naveed Ishaque,Roland Eils,Jens Peter Klussmann,Dana Holzinger,Christoph Plass,Amir Abdollahi,Kolja Freier,Wilko Weichert,Karim Zaoui,Jochen Hess,Jochen Hess +37 more
TL;DR: The data indicate that impaired RYR2 function by either somatic mutation or epigenetic silencing is a common event in HNSCC pathogenesis and detection of RYP2 expression and/or promoter methylation might enable risk assessment for malignant conversion of dysplastic lesions.
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Incidence of anatomical variations according to the International Frontal Sinus Anatomy Classification (IFAC) and their coincidence with radiological sings of opacification
Fabian Sommer,Thomas K. Hoffmann,Lena Harter,J Döscher,Sebastian Kleiner,Jörg Lindemann,Andreas Leunig +6 more
TL;DR: The aim of this study was to analyse a representative number of sinus CT scans to assess the incidence of anatomical variations according to the IFAC and to compare the results with previous classifications, and the coincidence of complex anatomical variations and radiological sings of opacification was investigated.
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Enhanced cellular migration and prolonged chondrogenic differentiation in decellularized cartilage scaffolds under dynamic culture conditions.
E Goldberg-Bockhorn,Ulla Wenzel,Marie-Nicole Theodoraki,J Döscher,R Riepl,Marlene C. Wigand,Cornelia Brunner,Martin Heßling,Thomas K. Hoffmann,Johann Kern,Nicole Rotter +10 more
TL;DR: In this paper, the authors used a custom-made glass bioreactor to enhance cell migration into decellularized porcine cartilage scaffolds (DECM) and mimic physiological conditions.
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Expression of Kallikrein-Related Peptidase 6 in Primary Mucosal Malignant Melanoma of the Head and Neck.
Julia Thierauf,Johannes A. Veit,Jochen K. Lennerz,Stephanie E. Weissinger,Annette Affolter,J Döscher,Christoph Bergmann,Andreas Knopf,Jennifer Grünow,Lisa Grünmüller,Cornelia Mauch,Peter K. Plinkert,Thomas K. Hoffmann,Jochen Hess +13 more
TL;DR: Increased levels of KLK6 are demonstrated for the first time in MMHN and the hypothesis that there might be a context-specific regulation and function of KL kallikrein-related peptidase 6 in mucosal melanoma is strengthened.