12 Papers
2 Citations
J. Cox is an academic researcher from Royal Sussex County Hospital. The author has contributed to research in topics: Blood pressure & Medicine. The author has an hindex of 6, co-authored 8 publications.
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Papers
Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial.
D. Mark Davies,Petrus J. de Vries,Simon R. Johnson,Deborah L. McCartney,Deborah L. McCartney,J. Cox,Andreas L. Serra,Peter Watson,Christopher J. Howe,Tim Doyle,Kate Pointon,Justin J. Cross,Anne E. Tattersfield,J. Chris Kingswood,Julian R. Sampson +14 more
TL;DR: This study showed sustained regression of renal angiomyolipomas in patients with tuberous sclerosis or sporadic LAM receiving 2 years of sirolimus treatment, suggesting possible effects on pulmonary function and neurocognition require further investigation.
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Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis.
D. Mark Davies,Simon R. Johnson,Anne E. Tattersfield,J. Chris Kingswood,J. Cox,Deborah L. McCartney,Tim Doyle,Frances Elmslie,Anand Saggar,Petrus J. de Vries,Julian R. Sampson +10 more
TL;DR: Constitutive activation of mTOR and its downstream targets occurs in lesions associated with tuberous sclerosis or lymphangioleiomyomatosis, suggesting that mTOR .
216
Low‐sodium haemodialysis without fluid removal improves blood pressure control in chronic haemodialysis patients
TL;DR: It is suggested that sodium overload and water overload may have independent effects on BP and that simple‐to‐achieve and modest changes in dialysate sodium could usefully augment the action of antihypertensives in dialysis patients.
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•Journal Article
How reproducible is diurnal blood pressure rhythm in patients with secondary (renal) hypertension
Covic A,David Goldsmith,Christopher K.T. Farmer,J. Cox,P. Dallyn,Paul Sharpstone,J. C. Kingswood +6 more
TL;DR: It is concluded that abnormalities of diurnal BP rhythm are reasonably consistent in patients with renal hypertension, especially as renal function declines and patients enter the renal replacement therapy programme.
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