J. C. Smith
University Hospital of Wales
15 Papers
207 Citations
J. C. Smith is an academic researcher from University Hospital of Wales. The author has contributed to research in topics: Arterial stiffness & Medicine. The author has an hindex of 9, co-authored 15 publications.
Chat about Author
Papers
Effects of GH replacement on endothelial function and large‐artery stiffness in GH‐deficient adults: a randomized, double‐blind, placebo‐controlled study
J. C. Smith,L. M. Evans,I Wilkinson,Jonathan Goodfellow,John R. Cockcroft,Maurice F. Scanlon,Jeffrey S. Davies +6 more
TL;DR: Hypopituitary adults with growth hormone deficiency (GHD) have an increased cardiovascular mortality, although the mechanisms remain unclear.
146
Impaired vasoreactivity in bodybuilders using androgenic anabolic steroids
H. Lane,Fergal M. Grace,J. C. Smith,Keith Morris,J.R. Cockcroft,Maurice F. Scanlon,J. S. Davies +6 more
TL;DR: Use of anabolic androgenic steroids is associated with sudden death, left ventricular hypertrophy, thrombo‐embolism and cerebro‐vascular events, and the cardiovascular implications of supraphysiological androgen levels requires further clarification.
76
The effects of depot long-acting somatostatin analog on central aortic pressure and arterial stiffness in acromegaly.
J. C. Smith,H C Lane,N. Davies,L. M. Evans,J.R. Cockcroft,Maurice F. Scanlon,Jeffrey S. Davies +6 more
TL;DR: Assessment of arterial stiffness in acromegalic subjects with and without active disease and the effects of Sandostatin LAR (OCT-LAR) on vascular function found large artery stiffening is reduced in cured acromegaly and partially reversed after pharmacological treatment of active disease.
44
Effects of GH on lipid peroxidation and neutrophil superoxide anion-generating capacity in hypopituitary adults with GH deficiency.
TL;DR: Untreated growth hormone deficiency is implicated in the increased cardiovascular risk associated with adult hypopituitarism and Oxidative stress, predisposing to lipid peroxidation, may be an important mediator of endothelial dysfunction, a pro‐atherogenic state associated withadult GHD.
27
Long-term remission following withdrawal of dopamine agonist therapy in subjects with microprolactinomas
M Biswas,J. C. Smith,Deepak R Jadon,P. Mcewan,D. A. Rees,L. M. Evans,Maurice F. Scanlon,J. S. Davies +7 more
- 01 Mar 2004
TL;DR: In this paper, the authors performed a retrospective analysis of 89 patients, 84 women and 5 men with a mean age of 33 years, who were analyzed in 67 patients treated with 0.5 to 3 mg cabergoline weekly and 22 others given 2.5-10 mg bromocriptine daily.
20