Massive evidence has now accumulated which indicates that the pituitary-adrenal cortical system responds sensitively to psychological influences. This evidence represents converging and reinforcing findings from diverse studies of many species, including man. It involved the use of many methods of e

A review of psychoendocrine research on the pituitary-adrenal cortical system.

Eosinophil response to aggressive behaviour in CFW albino mice

Physiological and Pathological Correlates of Population Density

Pathopoietic consequences of increasing population.

Osteoarthritis, having the morphological characteristics of degenerative joint disease in large animals, occurs spontaneously in Syrian hamsters (Silberberg, Saxton, Sperling, and McCay, 1952), rats (Sokoloff and Jay, 1956), guinea-pigs (Silverstein and Sokoloff, 1958), and mice. Hereditary factors are of major importance in its development in mice (Sokoloff, Crittenden, Yamamoto, and Jay, 1962), and variations in the frequency of the disorder among the several species also presumably depend on their genetic constitution. The present paper reports that an additional small rodent is prone to degenerative joint disease. Involvement of the intervertebral disks is particularly conspicuous, and sometimes causes incapacity and death in older animals. Praomys (subgenus Mastomys) natalensis (Davis, 1965) is a wild African rodent, intermediate in size and several other respects between rats and mice. This species has been studied under laboratory conditions in recent years because cancer frequently arises in its glandular stomach (Oettle, 1957; Snell and Stewart, in press). Mastomys is not inbred, but having been reared in captivity is undoubtedly more homogeneous genetically than in the wild. The lifespan is roughly comparable to that of the laboratory rat; the greatest age recorded in the present study was 38 months.

https://ard.bmj.com/content/annrheumdis/26/2/146.full.pdf

Degenerative joint disease in Praomys (Mastomys) natalensis.

Changes in the relative size of the nucleus in the intervertebral discs of stressed orkney voles (Microtus orcadensis)

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Changes in the relative size of the nucleus in the intervertebral discs of stressed orkney voles (Microtus orcadensis)