J. Breen
Harefield Hospital
14 Papers
69 Citations
J. Breen is an academic researcher from Harefield Hospital. The author has contributed to research in topics: Transplantation & Heart transplantation. The author has an hindex of 6, co-authored 14 publications.
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Papers
The Effects of Pre- and Post-transplant Anemia on 1-Year Survival After Cardiac Transplantation
TL;DR: Anemia before, but not after transplantation, is a common independent predictor of 1-year survival in cardiac transplant patients.
Pharmacokinetics of oral cyclosporine (Neoral) in heart transplant recipients during the immediate period after surgery.
Nicholas R. Banner,Olivier J. David,N. Leaver,Julie Davis,J. Breen,Atholl Johnston,Magdi H. Yacoub +6 more
TL;DR: Oral administration of Neoral may result in inadequate immunosuppression immediately after heart transplantation unless it is supplemented either by intravenous cyclosporine or by the use of an induction agent.
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Atp-binding Cassette Subfamily B Member 1 Polymorphisms Do Not Determine Cyclosporin Exposure, Acute Rejection or Nephrotoxicity After Heart Transplantation
Anne B. Taegtmeyer,J. Breen,John A. Smith,Margaret Burke,N. Leaver,Panagiotis Pantelidis,H. Lyster,Magdi H. Yacoub,Paul J.R. Barton,Nicholas R. Banner +9 more
TL;DR: The association of ABCB1 12/1236, 21/2677, and 26/3435 CC/GG/CC haplotype with increased CsA dose- and weight-adjusted Cs a trough concentrations in this group of adult white heart transplant recipients was not consistent over time and had no effect on the incidence of acute rejection or on the development of renal impairment.
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Effect of ABCB1 Genotype on Pre- and Post-Cardiac Transplantation Plasma Lipid Concentrations
Anne B. Taegtmeyer,J. Breen,John D. Smith,P. Rogers,Gerd A. Kullak-Ublick,Magdi H. Yacoub,Nicholas R. Banner,Nicholas R. Banner,Paul J.R. Barton +8 more
TL;DR: An association between ABCB1 haplotype and plasma fasting LDL cholesterol concentration was found in patients with advanced heart failure and was not seen 1 year after cardiac transplantation.
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Effect of Adenosine Monophosphate Deaminase-1 C34T Allele on the Requirement for Donor Inotropic Support and on the Incidence of Early Graft Dysfunction After Cardiac Transplantation
Anne B. Taegtmeyer,Anne B. Taegtmeyer,J. Breen,P. Rogers,Philip H. Johnson,John D. Smith,Ryzard T. Smolenski,Nicholas R. Banner,Nicholas R. Banner,Magdi H. Yacoub,Paul J.R. Barton +10 more
TL;DR: Possession of the AMPD1 T allele is associated with decreased inotropic requirements before heart donation and the incidence of early graft dysfunction was significantly higher in recipients who received AM PD1 T-allele-possessing organs resulting in worse 1-year survival.
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