J. Beer
4 Papers
23 Citations
J. Beer is an academic researcher. The author has contributed to research in topics: Amyloid & Gene. The author has an hindex of 2, co-authored 4 publications.
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Papers
Amyloid BA4 protein pathology is central to the cause of Alzheimer's disease
Konrad Beyreuther,Walter Schubert,Gerd Multhaup,J.M. Salbaum,J. Beer,Caroline Hilbich,G. König,Thomas Dyrks,Andreas Weidemann,Peter Fischer,D. Bunke,Ursula Mönning,N. Catteruccia,Hans Mechler,R. Prior,Tetsuyuki Kitamoto,E. Schlichtmann,E. Mack-Kühn,C.L. Masters +18 more
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Precursor of Alzheimer’s Disease (PAD) A4 Amyloid Protein
C. L. Masters,G. Multhaup,J. M. Salbaum,Andreas Weidemann,Thomas Dyrks,C. Hilbich,Peter Fischer,G. König,J. Beer,D. Bunke,Ursula Mönning,Stephanie J. Fuller,R. Martins,G. Simms,B. Rumble,K. Beyreuther +15 more
- 01 Jan 1988
TL;DR: Alzheimer’s disease affects 1% of the population of the Western world and 100% of aged individuals with Down's syndrome and it is characterized by neuronal dysfunction and depositions of amyloid A4 in the form of intracellular neurofibrillary tangles, extracellular plaques and cerebrovascular amyloids.
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The Molecular Basis of Cerebral Amyloidosis in Alzheimer’s Disease and the Unconventional Virus Diseases
Colin L. Masters,R. Martins,G. Simms,B. Rumble,Stephanie J. Fuller,L. Hutchinson,J. Beer,C. Hilbich,Thomas Dyrks,Peter Fischer,Andreas Weidemann,Ursula Mönning,G. Multhaup,Matthias Cramer,J. M. Salbaum,S. Wehr,K. Beyreuther +16 more
- 01 Jan 1988
TL;DR: The major protein subunit of the amyloid fibril in Alzheimer's disease is a small molecule of 42 residues (termed A4), which is derived from a larger precursor (PreA4), the gene for which is located on chromosome 21, in close proximity to the region involved in Down’s syndrome.
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