J. Barciszewski
Polish Academy of Sciences
23 Papers
148 Citations
J. Barciszewski is an academic researcher from Polish Academy of Sciences. The author has contributed to research in topics: Transfer RNA & RNA. The author has an hindex of 8, co-authored 23 publications.
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Papers
Structure of γ-conglutin: insight into the quaternary structure of 7S basic globulins from legumes.
Jaroslaw Czubinski,J. Barciszewski,Miroslaw Gilski,Kamil Szpotkowski,Janusz Debski,Eleonora Lampart-Szczapa,Mariusz Jaskolski +6 more
TL;DR: Structural elucidation of γ-conglutin will help to explain its physiological role, especially in the evolutionary context, and will guide further research into the hypoglycaemic activity of this protein in humans, with potential consequences for novel antidiabetic therapies.
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T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure
J. Barciszewski,Janusz Wisniewski,Robert Kolodziejczyk,Mariusz Jaskolski,Dariusz Rakus,Andrzej Dzugaj +5 more
- 01 Apr 2016
TL;DR: When crystallized in the absence of the allosteric inhibitor AMP, human muscle fructose-1,6-bisphosphatase has a totally unexpected quaternary structure of its active R form, with the two dimers of the homotetrameric molecule in a perpendicular orientation, in stark contrast to the coplanar arrangement of the closely related liver isozyme.
Higher plant 5S rRNAs share common secondary and tertiary structure. A new three domains model.
TL;DR: A new model of secondary and tertiary structure of higher plant 5S RNA is proposed, based on the results of partial digestion obtained with single- and double-strand RNA specific nucleases, and strongly supported by the observation that crude plant5S rRNA contains abundant RNA, identified as domain gamma of 5S r RNA.
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•Journal Article
Nucleotide sequence of tRNAPhe from the seeds of lupin (Lupinus luteus). Comparison of the major species with wheat germ tRNAPhe.
TL;DR: The nucleotide sequence of tRNAPhe of yellow lupin seeds (Lupinus luteus) is deduced from the composition of pancreatic and T1 ribonuclease digestion products and compared with tRN APhe of wheat germ.
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Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions.
TL;DR: The increase of DNA methylation resulting in global gene silencing and consecutive down regulation of gene expression after TMZ treatment may explain better glioblastoma patients’ survival.