J. A. Hayes
Boston University
30 Papers
731 Citations
J. A. Hayes is an academic researcher from Boston University. The author has contributed to research in topics: Cadmium chloride & Medicine. The author has an hindex of 15, co-authored 28 publications. Previous affiliations of J. A. Hayes include Tufts University & University of South Carolina.
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Papers
Myocardial Fibrosis and Stiffness With Hypertrophy and Heart Failure in the Spontaneously Hypertensive Rat
Chester H. Conrad,Wesley W. Brooks,J. A. Hayes,Subha Sen,Kathleen G. Robinson,Oscar H.L. Bing +5 more
TL;DR: The development of heart failure in the aging SHR is associated with marked myocardial fibrosis, increased passive stiffness, and impaired contractile function relative to age-matched nonfailing SHR and nonhypertensive control animals, suggesting that fibrosis or events underlying the connective tissue response are important in the transition from compensated hypertrophy to failure inthe SHR.
467
Comparison of transbronchial and open biopsies in chronic infiltrative lung diseases
TL;DR: It is concluded that TBB diagnoses of interstitial pneumonia, chronic inflammation, nonspecific reaction, and fibrosis are unreliable and often entirely misleading.
239
The spontaneously hypertensive rat as a model of the transition from compensated left ventricular hypertrophy to failure.
O. H. L. Bing,W.W. Brooks,W.W. Brooks,K. G. Robinson,K. G. Robinson,Mara Slawsky,Mara Slawsky,J. A. Hayes,J. A. Hayes,Sheldon E. Litwin,Subha Sen,Chester H. Conrad +11 more
TL;DR: Data suggest that impaired function is due to changes in the intrinsic properties of the myocardium and that the connective tissue response may play an important role and support for the use of the aging SHR as a model of the transition from compensated hypertrophy to failure.
231
Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin: pathology and stereology
TL;DR: An animal model of chronic interstitial pulmonary fibrosis produced in male golden hamsters by a single endotracheal instillation of 0.5 unit of bleomycin should be of value in studying cellular and biochemi cal events in the lung and in exploring various therapeutic strategies.
183
The pathology of elastase-induced panacinar emphysema in hamsters.
TL;DR: It is suggested that damage to elastic fibres may be an important element in the development of human panacinar emphysema, and that the damage could be one pathogenetic mechanism which produces damage of elastic fibre.
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