Ivana V. Yang
Anschutz Medical Campus
218 Papers
932 Citations
Ivana V. Yang is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 47, co-authored 178 publications. Previous affiliations of Ivana V. Yang include Colorado School of Public Health & University of Colorado Boulder.
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Papers
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
Yasushi Okazaki,Masaaki Furuno,Takeya Kasukawa,Jun Adachi,Hidemasa Bono,S. Kondo,Itoshi Nikaido,Naoki Osato,Rintaro Saito,Harukazu Suzuki,Itaru Yamanaka,H. Kiyosawa,Ken Yagi,Yasuhiro Tomaru,Yuki Hasegawa,A. Nogami,Christian Schönbach,Takashi Gojobori,Richard M. Baldarelli,David P. Hill,Carol J. Bult,David A. Hume,John Quackenbush,Lynn M. Schriml,Alexander Kanapin,Hideo Matsuda,Serge Batalov,Kirk W. Beisel,Judith A. Blake,Dirck W. Bradt,Vladimir Brusic,Cyrus Chothia,Lori E. Corbani,S. Cousins,Emiliano Dalla,Tommaso A. Dragani,Colin F. Fletcher,Colin F. Fletcher,Alistair R. R. Forrest,K. S. Frazer,Terry Gaasterland,Manuela Gariboldi,Carmela Gissi,Adam Godzik,Julian Gough,Sean M. Grimmond,Stefano Gustincich,Nobutaka Hirokawa,Ian J. Jackson,Erich D. Jarvis,Akio Kanai,Hideya Kawaji,Hideya Kawaji,Yuka Imamura Kawasawa,Rafal M. Kedzierski,Benjamin L. King,Akihiko Konagaya,Igor V. Kurochkin,Yong-Hwan Lee,Boris Lenhard,Paul A. Lyons,Donna Maglott,Lois J. Maltais,Luigi Marchionni,Louise M. McKenzie,Harukata Miki,Takeshi Nagashima,Koji Numata,Toshihisa Okido,William J. Pavan,Geo Pertea,Graziano Pesole,Nikolai Petrovsky,Ramesh S. Pillai,Joan Pontius,D. Qi,Sridhar Ramachandran,Timothy Ravasi,Jonathan C. Reed,Deborah J Reed,Jeffrey G. Reid,Brian Z. Ring,M. Ringwald,Albin Sandelin,Claudio Schneider,Colin A. Semple,Mitsutoshi Setou,K. Shimada,Razvan Sultana,Yoichi Takenaka,Martin S. Taylor,Rohan D. Teasdale,Masaru Tomita,Roberto Verardo,Lukas Wagner,Claes Wahlestedt,Y. Wang,Yoshiki Watanabe,Christine A. Wells,Laurens G. Wilming,Anthony Wynshaw-Boris,Masashi Yanagisawa,Ivana V. Yang,L. Yang,Zheng Yuan,Mihaela Zavolan,Yunhui Zhu,Anne M. Zimmer,Piero Carninci,N. Hayatsu,Tomoko Hirozane-Kishikawa,Hideaki Konno,M. Nakamura,Naoko Sakazume,K. Sato,Toshiyuki Shiraki,Kazunori Waki,Jun Kawai,Katsunori Aizawa,Takahiro Arakawa,S. Fukuda,A. Hara,W. Hashizume,K. Imotani,Y. Ishii,Masayoshi Itoh,Ikuko Kagawa,A. Miyazaki,K. Sakai,D. Sasaki,K. Shibata,Akira Shinagawa,Ayako Yasunishi,Masayasu Yoshino,Robert H. Waterston,Eric S. Lander,Jane Rogers,Ewan Birney,Yoshihide Hayashizaki +138 more
TL;DR: The present work, completely supported by physical clones, provides the most comprehensive survey of a mammalian transcriptome so far, and is a valuable resource for functional genomics.
A common MUC5B promoter polymorphism and pulmonary fibrosis
Max A. Seibold,Anastasia L. Wise,Marcy C. Speer,Mark P. Steele,Kevin K. Brown,James E. Loyd,Tasha E. Fingerlin,Weiming Zhang,Gunnar Gudmundsson,Steve D. Groshong,Christopher M. Evans,Stavros Garantziotis,Kenneth B. Adler,Burton F. Dickey,Roland M. du Bois,Ivana V. Yang,Aretha Herron,Dolly Kervitsky,Janet Talbert,Cheryl Markin,Joungjoa Park,Anne L. Crews,Susan Slifer,Scott S. Auerbach,Michelle G. Roy,Jia Lin,Corinne E. Hennessy,Marvin I. Schwarz,David A. Schwartz +28 more
TL;DR: The findings suggest that dysregulated MUC5B expression in the lung may be involved in the pathogenesis of pulmonary fibrosis, and a common polymorphism in the promoter of M UC5B is associated with familial interstitial pneumonia and idiopathic pulmonary fibrot.
Muc5b is required for airway defence
Michelle G. Roy,Alessandra Livraghi-Butrico,Ashley A. Fletcher,Melissa M. McElwee,Scott E. Evans,Ryan M. Boerner,Samantha N. Alexander,Lindsey K. Bellinghausen,Alfred S. Song,Youlia Petrova,Michael J. Tuvim,Roberto Adachi,Irlanda Romo,Andrea S. Bordt,M. Gabriela Bowden,M. Gabriela Bowden,Joseph H. Sisson,Prescott G. Woodruff,David J. Thornton,Karine Rousseau,Maria Miguelina De La Garza,Seyed Javad Moghaddam,Harry Karmouty-Quintana,Michael R. Blackburn,Scott M. Drouin,C. William Davis,Kristy A. Terrell,Barbara R. Grubb,Wanda K. O'Neal,Sonia C. Flores,Adela Cota-Gomez,Catherine A. Lozupone,Jody Donnelly,Alan M. Watson,Corinne E. Hennessy,Rebecca C. Keith,Ivana V. Yang,Lea Barthel,Peter M. Henson,William J. Janssen,David A. Schwartz,Richard C. Boucher,Burton F. Dickey,Christopher M. Evans,Christopher M. Evans +44 more
TL;DR: It is shown that mouse Muc5b (but not MUC5ac) is required for MCC, for controlling infections in the airways and middle ear, and for maintaining immune homeostasis in mouse lungs, whereas Muc 5ac is dispensable.
Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Alexander G. Bick,Joshua S. Weinstock,Satish K. Nandakumar,Satish K. Nandakumar,Charles P. Fulco,Charles P. Fulco,Erik L. Bao,Erik L. Bao,Seyedeh M. Zekavat,Seyedeh M. Zekavat,Mindy D. Szeto,Xiaotian Liao,Xiaotian Liao,Matthew Leventhal,Joseph Nasser,Kyle Chang,Cecelia A. Laurie,Bala Bharathi Burugula,Christopher J. Gibson,Amy E. Lin,Margaret A. Taub,François Aguet,Kristin G. Ardlie,Braxton D. Mitchell,Braxton D. Mitchell,Kathleen C. Barnes,Kathleen C. Barnes,Arden Moscati,Myriam Fornage,Susan Redline,Susan Redline,Susan Redline,Bruce M. Psaty,Edwin K. Silverman,Edwin K. Silverman,Scott T. Weiss,Scott T. Weiss,Nicholette D. Palmer,Ramachandran S. Vasan,Esteban G. Burchard,Sharon L.R. Kardia,Jiang He,Robert C. Kaplan,Robert C. Kaplan,Nicholas L. Smith,Nicholas L. Smith,Nicholas L. Smith,Donna K. Arnett,David A. Schwartz,Adolfo Correa,Mariza de Andrade,Xiuqing Guo,Barbara A. Konkle,Brian Custer,Juan M. Peralta,Hongsheng Gui,Deborah A. Meyers,Stephen T. McGarvey,Ida Yii-Der Chen,M. Benjamin Shoemaker,Patricia A. Peyser,Jai G. Broome,Stephanie M. Gogarten,Fei Fei Wang,Quenna Wong,May E. Montasser,Michelle Daya,Eimear E. Kenny,Kari E. North,Lenore J. Launer,Brian E. Cade,Brian E. Cade,Joshua C. Bis,Michael H. Cho,Michael H. Cho,Jessica Lasky-Su,Jessica Lasky-Su,Donald W. Bowden,L. Adrienne Cupples,Angel C.Y. Mak,Lewis C. Becker,Jennifer A. Smith,Tanika N. Kelly,Stella Aslibekyan,Susan R. Heckbert,Susan R. Heckbert,Hemant K. Tiwari,Ivana V. Yang,John A. Heit,Steven A. Lubitz,Steven A. Lubitz,Jill M. Johnsen,Joanne E. Curran,Sally E. Wenzel,Daniel E. Weeks,Dabeeru C. Rao,Dawood Darbar,Jee-Young Moon,Russell P. Tracy,Erin J Buth,Nicholas Rafaels,Ruth J. F. Loos,Peter Durda,Yongmei Liu,Lifang Hou,Jiwon Lee,Priyadarshini Kachroo,Priyadarshini Kachroo,Barry I. Freedman,Daniel Levy,Lawrence F. Bielak,James E. Hixson,James S. Floyd,Eric A. Whitsel,Patrick T. Ellinor,Patrick T. Ellinor,Marguerite R. Irvin,Tasha E. Fingerlin,Laura M. Raffield,Sebastian M. Armasu,Marsha M. Wheeler,Ester Cerdeira Sabino,John Blangero,L. Keoki Williams,Bruce D. Levy,Bruce D. Levy,Wayne Huey-Herng Sheu,Dan M. Roden,Eric Boerwinkle,Eric Boerwinkle,JoAnn E. Manson,JoAnn E. Manson,Rasika A. Mathias,Pinkal Desai,Kent D. Taylor,Andrew D. Johnson,Paul L. Auer,Charles Kooperberg,Cathy C. Laurie,Thomas W. Blackwell,Albert V. Smith,Hongyu Zhao,Ethan M. Lange,Leslie A. Lange,Stephen S. Rich,Jerome I. Rotter,James G. Wilson,James G. Wilson,Paul Scheet,Jacob O. Kitzman,Eric S. Lander,Eric S. Lander,Eric S. Lander,Jesse M. Engreitz,Jesse M. Engreitz,Benjamin L. Ebert,Alexander P. Reiner,Alexander P. Reiner,Siddhartha Jaiswal,Gonçalo R. Abecasis,Gonçalo R. Abecasis,Vijay G. Sankaran,Vijay G. Sankaran,Sekar Kathiresan,Pradeep Natarajan,Pradeep Natarajan +165 more
TL;DR: Analysis of high-coverage whole-genome sequences from 97,691 participants of diverse ancestries in the National Heart, Lung, and Blood Institute Trans-omics for Precision Medicine programme enables simultaneous identification of germline and somatic mutations that predispose individuals to clonal expansion of haematopoietic stem cells.
Comb-p
TL;DR: This work provides validation and example uses on bisulfite-seq with P-values from Fisher's exact test, tiled methylation probes using a linear model and Dam-ID for chromatin binding using moderated t-statistics.
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