Ivan Soler
University of Pennsylvania
10 Papers
22 Citations
Ivan Soler is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Medicine & Hippocampal formation. The author has an hindex of 2, co-authored 7 publications. Previous affiliations of Ivan Soler include Children's Hospital of Philadelphia.
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Papers
Stimulation of entorhinal cortex–dentate gyrus circuitry is antidepressive
Sanghee Yun,Sanghee Yun,Ryan P. Reynolds,Iraklis Petrof,Alicia White,Phillip D. Rivera,Phillip D. Rivera,Amir Segev,Adam D. Gibson,Maiko Suarez,Matthew J. DeSalle,Naoki Ito,Naoki Ito,Shibani Mukherjee,Devon R. Richardson,Catherine E. Kang,Rebecca C. Ahrens-Nicklas,Ivan Soler,Ivan Soler,Dane M. Chetkovich,Dane M. Chetkovich,Saïd Kourrich,Douglas A. Coulter,Douglas A. Coulter,Amelia J. Eisch,Amelia J. Eisch,Amelia J. Eisch +26 more
TL;DR: It is shown that molecular targeting and chemogenetic stimulation of Ent neurons induce antidepressive-like effects in mice, and the power and potential of Ent glutamatergic afferent stimulation—previously well-known for its ability to influence learning and memory—for MDD treatment is emphasized.
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Multi-domain cognitive assessment of male mice shows space radiation is not harmful to high-level cognition and actually improves pattern separation
Cody W. Whoolery,Sanghee Yun,Sanghee Yun,Ryan P. Reynolds,Ryan P. Reynolds,Melanie J. Lucero,Ivan Soler,Fionya H. Tran,Naoki Ito,Naoki Ito,Rachel L. Redfield,Devon R. Richardson,Hung Ying Shih,Phillip D. Rivera,Phillip D. Rivera,Benjamin P C Chen,Shari G. Birnbaum,Ann M. Stowe,Ann M. Stowe,Amelia J. Eisch +19 more
TL;DR: Surprisingly, 56 Fe irradiation improved performance on a dentate gyrus-reliant pattern separation task; irradiated mice learned faster and were more accurate than controls; these data urge revisitation of the broadly-held view that space radiation is detrimental to cognition.
Multi-Domain Touchscreen-Based Cognitive Assessment of C57BL/6J Female Mice Shows Whole-Body Exposure to 56Fe Particle Space Radiation in Maturity Improves Discrimination Learning Yet Impairs Stimulus-Response Rule-Based Habit Learning.
Ivan Soler,Sanghee Yun,Sanghee Yun,Sanghee Yun,Ryan P. Reynolds,Ryan P. Reynolds,Cody W. Whoolery,Fionya H. Tran,Priya L. Kumar,Yuying Rong,Matthew J. DeSalle,Adam D. Gibson,Ann M. Stowe,Frederico C Kiffer,Amelia J. Eisch +14 more
TL;DR: In this paper, a mouse cognitive touchscreen battery was used to evaluate the effect of space radiation on the performance of a discriminative task (location discrimination reversal) and a rule-based task (rule-based learning).
Effects of a 33-ion sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure.
Frederico C Kiffer,Krishna Luitel,Fionya H. Tran,Riya A Patel,Catalina S Guzman,Ivan Soler,Rui Xiao,Jerry W. Shay,Sanghee Yun,Sanghee Yun,Amelia J. Eisch +10 more
TL;DR: In this paper, the effects of galactic cosmic radiation (GCR) exposure on the central nervous system (CNS) were investigated in a mouse with a 6-mo-old C57BL/6-J male.
13
Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity
Sanghee Yun,Ivan Soler,Fionya H. Tran,Harley A. Haas,Raymon Shi,Grace L. Bancroft,Maiko Suarez,Chris R. de Santis,Ryan P. Reynolds,Amelia J. Eisch +9 more
TL;DR: In this paper , the authors showed that the activity of LEC fan cells that directly project to the DG (LEC➔DG neurons) regulates behavioral pattern separation or cognitive flexibility.