Irit Sagi
Weizmann Institute of Science
187 Papers
1.1K Citations
Irit Sagi is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Extracellular matrix & Matrix metalloproteinase. The author has an hindex of 47, co-authored 175 publications. Previous affiliations of Irit Sagi include Max Planck Society & University of Illinois at Urbana–Champaign.
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Papers
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
Ayuko Hoshino,Ayuko Hoshino,Han Sang Kim,Han Sang Kim,Linda Bojmar,Linda Bojmar,Linda Bojmar,Kofi Ennu Gyan,Michele Cioffi,Jonathan M. Hernandez,Jonathan M. Hernandez,Jonathan M. Hernandez,Constantinos P. Zambirinis,Constantinos P. Zambirinis,Gonçalo Rodrigues,Gonçalo Rodrigues,Henrik Molina,Søren Heissel,Milica Tesic Mark,Loïc Steiner,Loïc Steiner,Alberto Benito-Martin,Serena Lucotti,Angela Di Giannatale,Katharine Offer,Miho Nakajima,Caitlin Williams,Laura Nogués,Laura Nogués,Fanny A. Pelissier Vatter,Ayako Hashimoto,Ayako Hashimoto,Ayako Hashimoto,Alexander E. Davies,Daniela Freitas,Daniela Freitas,Candia M. Kenific,Yonathan Ararso,Weston Buehring,Pernille Lauritzen,Yusuke Ogitani,Kei Sugiura,Kei Sugiura,Naoko Takahashi,Maša Alečković,Kayleen A. Bailey,Joshua S. Jolissant,Joshua S. Jolissant,Huajuan Wang,Ashton Harris,L. Miles Schaeffer,Guillermo García-Santos,Guillermo García-Santos,Zoe Posner,Vinod P. Balachandran,Yasmin Khakoo,G. Praveen Raju,Avigdor Scherz,Irit Sagi,Ruth Scherz-Shouval,Yosef Yarden,Moshe Oren,Mahathi Malladi,Mary Petriccione,Kevin C. De Braganca,Maria Donzelli,Cheryl Fischer,Stephanie Vitolano,Geraldine P. Wright,Lee Ganshaw,Mariel Marrano,Amina Ahmed,Joe DeStefano,Enrico Danzer,Michael H.A. Roehrl,Norman J. Lacayo,Theresa C. Vincent,Theresa C. Vincent,Martin R. Weiser,Mary S. Brady,Paul A. Meyers,Leonard H. Wexler,Srikanth R. Ambati,Alexander J. Chou,Emily K. Slotkin,Shakeel Modak,Stephen S. Roberts,Ellen M. Basu,Daniel Diolaiti,Benjamin A. Krantz,Benjamin A. Krantz,Fatima Cardoso,Amber L. Simpson,Michael F. Berger,Charles M. Rudin,Diane M. Simeone,Maneesh Jain,Cyrus M. Ghajar,Surinder K. Batra,Ben Z. Stanger,Jack D. Bui,Kristy A. Brown,Vinagolu K. Rajasekhar,John H. Healey,Maria de Sousa,Maria de Sousa,Kim Kramer,Sujit Sheth,Jeanine Baisch,Virginia Pascual,Todd E. Heaton,Michael P. La Quaglia,David J. Pisapia,Robert E. Schwartz,Haiying Zhang,Yuan Liu,Arti Shukla,Laurence Blavier,Yves A. DeClerck,Mark A. LaBarge,Mina J. Bissell,Thomas C. Caffrey,Paul M. Grandgenett,Michael A. Hollingsworth,Jacqueline Bromberg,Jacqueline Bromberg,Bruno Costa-Silva,Héctor Peinado,Yibin Kang,Benjamin A. Garcia,Eileen M. O'Reilly,David P. Kelsen,Tanya M. Trippett,David R. Jones,Irina Matei,William R. Jarnagin,David Lyden +136 more
TL;DR: EVP proteins can serve as reliable biomarkers for cancer detection and determining cancer type, and a panel of tumor-type-specific EVP proteins in TEs and plasma are defined, which can classify tumors of unknown primary origin.
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The extracellular matrix protein agrin promotes heart regeneration in mice
Elad Bassat,Yara Eid Mutlak,Alex Genzelinakh,Ilya Y. Shadrin,Kfir Baruch Umansky,Oren Yifa,David Kain,Dana Rajchman,John Leach,Daria Riabov Bassat,Yael Udi,Rachel Sarig,Irit Sagi,James F. Martin,Nenad Bursac,Shenhav Cohen,Eldad Tzahor +16 more
TL;DR: In vivo, a single administration of agrin promotes cardiac regeneration in adult mice after myocardial infarction, although the degree of cardiomyocyte proliferation observed in this model suggests that there are additional therapeutic mechanisms.
Transformation mechanism of amorphous calcium carbonate into calcite in the sea urchin larval spicule
Yael Politi,Rebecca A. Metzler,Mike Abrecht,Benjamin Gilbert,Fred H. Wilt,Irit Sagi,Lia Addadi,Steve Weiner,Pupa U. P. A. Gilbert +8 more
TL;DR: X-ray photoelectron emission spectromicroscopy resolves 3 distinct mineral phases: An initial short-lived, presumably hydrated ACC phase, followed by an intermediate transient form of ACC, and finally the biogenic crystalline calcite phase.
424
Choosing the Crystallization Path Less Traveled
TL;DR: In this article, the authors use a most unexpected strategy for forming large single crystals such as those that make up mineralized skeletal parts, which allows organisms to mold the crystals into unusual shapes and orient them at will.
341
Tumor macrophages are pivotal constructors of tumor collagenous matrix.
Ran Afik,Ehud Zigmond,Milena Vugman,Mordehay Klepfish,Elee Shimshoni,Metsada Pasmanik-Chor,Anjana Shenoy,Elad Bassat,Zamir Halpern,Tamar Geiger,Irit Sagi,Chen Varol +11 more
TL;DR: Tumor-associated macrophages are pivotal constructors of the tumoral ECM structure and molecular composition and orchestrate the buildup of the tumorigenic collagenous ECM niche.