Iris Ziegler
University of Düsseldorf
6 Papers
13 Citations
Iris Ziegler is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Nerve fiber & Diabetes mellitus. The author has an hindex of 5, co-authored 6 publications.
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Papers
Early Detection of Nerve Fiber Loss by Corneal Confocal Microscopy and Skin Biopsy in Recently Diagnosed Type 2 Diabetes
Dan Ziegler,Nikolaos Papanas,Andrey Zhivov,Stephan Allgeier,Karsten Winter,Iris Ziegler,Jutta Brüggemann,Alexander Strom,Sabine Peschel,Bernd Köhler,Oliver Stachs,Rudolf F. Guthoff,Michael Roden +12 more
TL;DR: CCM and skin biopsy both detect nerve fiber loss in recently diagnosed type 2 diabetes, but largely in different patients, suggesting a patchy manifestation pattern of small fiber neuropathy.
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Lower serum extracellular superoxide dismutase levels are associated with polyneuropathy in recent-onset diabetes.
Alexander Strom,Kirti Kaul,Jutta Brüggemann,Iris Ziegler,Ilka Rokitta,Sonja Püttgen,Julia Szendroedi,Karsten Müssig,Michael Roden,Dan Ziegler +9 more
TL;DR: Several biomarkers of oxidative stress are altered in recent-onset diabetes, with only a lower SOD3 concentration being linked to the presence of DSPN, suggesting a role for reduced extracellular antioxidative defense against superoxide in the early development of D SPN.
Spatial analysis improves the detection of early corneal nerve fiber loss in patients with recently diagnosed type 2 diabetes.
Dan Ziegler,Karsten Winter,Alexander Strom,Andrey Zhivov,Stephan Allgeier,Nikolaos Papanas,Iris Ziegler,Jutta Brüggemann,Bernd Ringel,Sabine Peschel,Bernd Köhler,Oliver Stachs,Rudolf F. Guthoff,Michael Roden +13 more
TL;DR: Spatial point pattern analysis reveals increased clustering of early CNF loss and substantially improves its detection when combined with a conventional CCM measure in patients with recently diagnosed type 2 diabetes.
Overexpression of cutaneous mitochondrial superoxide dismutase in recent-onset type 2 diabetes.
Dan Ziegler,Alexander Strom,Jutta Brüggemann,Iris Ziegler,Bernd Ringel,Sonja Püttgen,Michael Roden +6 more
TL;DR: Cutaneous antioxidative defence is enhanced in relation to the duration of diabetes and is linked to a cardiac sympathovagal imbalance towards a sympathetic predominance in individuals with recently diagnosed type 2 diabetes without evidence of endothelial cell damage.
Early detection of nerve fiber loss by in vivo corneal confocal microscopy in recently diagnosed type 2 diabetic patients
Dan Ziegler,Andrey Zhivov,Stephan Allgeier,Karsten Winter,Nikolaos Papanas,Iris Ziegler,Sabine Peschel,Bernd Koehler,Oliver Stachs,Rainer Guthoff,Michael Roden +10 more
- 01 Jan 2012
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