Ioannis Zerdes
Karolinska Institutet
53 Papers
107 Citations
Ioannis Zerdes is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 10, co-authored 30 publications. Previous affiliations of Ioannis Zerdes include Karolinska University Hospital & RMIT University.
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Papers
Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations.
Ioannis Zerdes,Alexios Matikas,Alexios Matikas,Jonas Bergh,Jonas Bergh,George Z. Rassidakis,George Z. Rassidakis,Theodoros Foukakis,Theodoros Foukakis +8 more
TL;DR: Understanding the regulation of PD-L1 in cancer will be of utmost importance for defining its role as predictive marker but also for optimizing strategies for cancer immunotherapy.
Prognostic Implications of PD-L1 Expression in Breast Cancer: Systematic Review and Meta-analysis of Immunohistochemistry and Pooled Analysis of Transcriptomic Data
Alexios Matikas,Ioannis Zerdes,John Lövrot,Francois Richard,Christos Sotiriou,Jonas Bergh,Jonas Bergh,Antonios Valachis,Theodoros Foukakis,Theodoros Foukakis +9 more
TL;DR: The largest to the authors' knowledge meta-analysis on the subject informs on PD-L1 protein positivity rates and its prognostic value in breast cancer, and PD- L1 gene expression is a promising prognostic factor, especially in basal-like breast cancer.
Non-epithelial Ovarian Cancer: Elucidating Uncommon Gynaecological Malignancies
Stergios Boussios,George Zarkavelis,Esmeralda Seraj,Ioannis Zerdes,Konstantina Tatsi,George Pentheroudakis +5 more
TL;DR: This review summarizes the published literature on the incidence, clinical presentation, pathology, therapeutic interventions, survival and prognostic factors of each sub-type of non-epithelial ovarian cancers.
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SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12.
Patricia González-Rodríguez,Pinelopi Engskog-Vlachos,Hanzhao Zhang,Hanzhao Zhang,Adriana-Natalia Murgoci,Ioannis Zerdes,Bertrand Joseph +6 more
TL;DR: These findings bring further argument for considering the SETD2 gene status of ccRCC tumors, when therapeutic interventions, such as targeting the autophagic process, are considered to combat these kidney cancers.
The Role of Statins in Prevention of Preeclampsia: A Promise for the Future?
Vasiliki Katsi,Georgios Georgountzos,Manolis S. Kallistratos,Ioannis Zerdes,Thomas Makris,Athanasios J. Manolis,Petros Nihoyannopoulos,Dimitris Tousoulis +7 more
TL;DR: The current data is summarized, the potential future role of statins in the prevention and management of preeclampsia is delineated and Pravastatin seems to have a safer pharmacokinetic profile compared to other statins.