Ioannis Kramvis
VU University Amsterdam
10 Papers
19 Citations
Ioannis Kramvis is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Prefrontal cortex & Hippocampus. The author has an hindex of 6, co-authored 10 publications.
Chat about Author
Papers
Sensitive time-windows for susceptibility in neurodevelopmental disorders.
TL;DR: It is proposed that time-restricted windows for impaired synaptic phenotypes exist in NDDs, akin to critical periods during normal sensory development in the brain, and may indicate vulnerable periods when the brain is more susceptible to current therapeutic treatments.
110
Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats
Danai Riga,Ioannis Kramvis,Maija Kreetta Koskinen,Pieter van Bokhoven,Johanneke E. van der Harst,Johanneke E. van der Harst,Tim S. Heistek,A. Jaap Timmerman,Pim van Nierop,Roel C. van der Schors,Anton W. Pieneman,Anouk de Weger,Yvar van Mourik,Anton N. M. Schoffelmeer,Mansvelder Hd,Rhiannon M. Meredith,Witte J.G. Hoogendijk,August B. Smit,Sabine Spijker +18 more
TL;DR: The data reveal a causal link between increased hippocampal extracellular matrix and the cognitive deficits associated with a chronic depressive-like state in rats exposed to SDPS.
108
Memory strength gates the involvement of a CREB-dependent cortical fear engram in remote memory
Mariana R. Matos,Esther Visser,Ioannis Kramvis,Rolinka J. van der Loo,Titia Gebuis,Robbert Zalm,Priyanka Rao-Ruiz,Huibert D. Mansvelder,August B. Smit,Michel C. van den Oever +9 more
TL;DR: It is demonstrated that memory consolidation by mPFC engram cells requires CREB-mediated transcription, with the functionality of this network hub being gated by memory strength.
Hyperactivity, perseveration and increased responding during attentional rule acquisition in the Fragile X mouse model
TL;DR: Normal inhibitory control and sustained attention are demonstrated but heightened perseveration, responding, and hyperactivity during novel rule acquisition and during exposure to novel environments in Fragile X knockout mice are demonstrated.
Gpr158 Deficiency Impacts Hippocampal CA1 Neuronal Excitability, Dendritic Architecture, and Affects Spatial Learning
Demirhan Çetereisi,Ioannis Kramvis,Titia Gebuis,Rolinka J. van der Loo,Yvonne Gouwenberg,Huibert D. Mansvelder,Ka Wan Li,August B. Smit,Sabine Spijker +8 more
TL;DR: The hippocampal neuronal morphology deficits appear to support the impairments in spatial memory acquisition observed in Gpr158 KO mice, providing first evidence of significant disruptions in hippocampal CA1 neuronal dendritic architecture and physiology.