Ingo Volkmann
Hochschule Hannover
24 Papers
26 Citations
Ingo Volkmann is an academic researcher from Hochschule Hannover. The author has contributed to research in topics: Medicine & Gene silencing. The author has an hindex of 9, co-authored 21 publications. Previous affiliations of Ingo Volkmann include Pasteur Institute & Hannover Medical School.
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Papers
Regulation and function of miRNA-21 in health and disease
TL;DR: Due to the critical functions of its target proteins in various signaling pathways, miR-21 has become an attractive target for genetic and pharmacological modulation in various disease conditions.
580
Transforming Growth Factor-β–Induced Endothelial-to-Mesenchymal Transition Is Partly Mediated by MicroRNA-21
TL;DR: TGF-&bgr;-mediated EndMT is regulated at least in part by miR-21 via the phosphatase and tensin homolog/Akt pathway, and antifibrotic effects of miR -21 antagonism are partly mediated by blocking EndMT under stress conditions.
297
Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients.
Johan M. Lorenzen,Ingo Volkmann,Jan Fiedler,Mascha Schmidt,Irina Scheffner,Hermann Haller,Wilfried Gwinner,Thomas Thum +7 more
TL;DR: Urinary miR‐210 levels identify patients with acute rejection and predict long‐term kidney function, and may serve as a novel biomarker of acute kidney rejection.
207
Diabetes-Associated MicroRNAs in Pediatric Patients With Type 1 Diabetes Mellitus: A Cross-Sectional Cohort Study
Julia Osipova,Dagmar-Christiane Fischer,Seema Dangwal,Ingo Volkmann,Christian Widera,Katrin Schwarz,Johan M. Lorenzen,Corinna Schreiver,Ulrike Jacoby,Mirjam Heimhalt,Thomas Thum,Dieter Haffner +11 more
TL;DR: Type 1 diabetic pediatric patients revealed a significant deregulation ofmiR-21, miR-126, and miR -210 in plasma and urinary samples, which might indicate an early onset of diabetic-associated diseases.
151
SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway
Regalla Kumarswamy,Alexander R. Lyon,Ingo Volkmann,A Mills,Julia Bretthauer,Aanchal Pahuja,Cornelia Geers-Knörr,Theresia Kraft,Roger J. Hajjar,Kenneth T. MacLeod,Sian E. Harding,Thomas Thum +11 more
TL;DR: SerCA2a gene therapy of failing hearts restores miR-1 expression by an Akt/FoxO3A-dependent pathway, which is associated with normalized NCX1 expression and improved cardiac function.