Ingo Bechman
Leipzig University
2 Papers
Ingo Bechman is an academic researcher from Leipzig University. The author has contributed to research in topics: Chemokine receptor & Proinflammatory cytokine. The author has an hindex of 2, co-authored 2 publications.
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Papers
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrier
Judith Hauptmann,Lisa Johann,Federico Marini,Maja Kitic,Elisa Colombo,Ilgiz A. Mufazalov,Martin Krueger,Khalad Karram,Sonja Moos,Sonja Moos,Florian Wanke,Florian Wanke,Florian C. Kurschus,Florian C. Kurschus,Matthias Klein,Silvia Cardoso,Judith Strauß,Subhashini Bolisetty,Fred Lühder,Markus Schwaninger,Harald Binder,Ingo Bechman,Tobias Bopp,Anupam Agarwal,Miguel P. Soares,Tommy Regen,Ari Waisman +26 more
TL;DR: It is found that IL-1 signaling in microglia and astrocytes is redundant for the development of EAE, whereas theIL-1R1 deletion in BBB-ECs markedly ameliorated disease severity, and Mechanistically, this data emphasize a functional crosstalk of BBb-EC IL- 1 signaling and HO-1, controlling the transcription of downstream proinflammatory genes promoting the pathogenesis of autoimmune neuroinflammation.
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy.
Roxana O. Carare,Roxana Aldea,Nivedita Agarwal,Brian J. Bacskai,Ingo Bechman,Delphine Boche,Guojun Bu,Diederik Bulters,Alt Clemens,Scott E. Counts,Mony J. de Leon,Per Kristian Eide,Silvia Fossati,Steven M. Greenberg,Edith Hamel,Cheryl A. Hawkes,Maya Koronyo-Hamaoui,Atticus H. Hainsworth,David M. Holtzman,Masafumi Ihara,Angela L. Jefferson,Raj N. Kalaria,Christopher M. Kipps,Katja M. Kanninen,Ville Leinonen,JoAnne McLaurin,Scott Miners,Tarja Malm,James A. R. Nicoll,James A. R. Nicoll,Fabrizio Piazza,Gesine Paul,Steven M. Rich,Satoshi Saito,Andy Y Shih,Henrieta Scholtzova,Heather M. Snyder,Peter J. Snyder,Finnbogi Rutur Thormodsson,Susanne J. van Veluw,Roy O. Weller,David J. Werring,Donna M. Wilcock,Mark R. Wilson,Berislav V. Zlokovic,Ajay Verma +45 more
TL;DR: The rationale that has led to the establishment of the Clearance of Interstitial Fluid (ISF) and CSF (CLIC) group, within the Vascular Professional Interest Area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment is introduced.