Ines Sherifi
Cornell University
18 Papers
152 Citations
Ines Sherifi is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & Valve replacement. The author has an hindex of 8, co-authored 18 publications. Previous affiliations of Ines Sherifi include University of Toronto & Brigham and Women's Hospital.
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Papers
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
Omid C. Farokhzad,Jianjun Cheng,Jianjun Cheng,Benjamin A. Teply,Ines Sherifi,Sangyong Jon,Philip W. Kantoff,Jerome P. Richie,Robert Langer,Robert Langer +9 more
TL;DR: The potential utility of nanoparticle-aptamer bioconjugates for a therapeutic application is demonstrated and remarkable efficacy and reduced toxicity as measured by mean body weight loss (BWL) in vivo are demonstrated.
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Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery
Jianjun Cheng,Benjamin A. Teply,Benjamin A. Teply,Ines Sherifi,Ines Sherifi,Josephine Sung,Gaurav Luther,Frank X. Gu,Etgar Levy-Nissenbaum,Etgar Levy-Nissenbaum,Aleksandar Filip Radovic-Moreno,Robert Langer,Omid C. Farokhzad,Omid C. Farokhzad +13 more
TL;DR: It is found that NP mean volumetric size correlates linearly with polymer concentration for NPs between 70 and 250 nm in diameter and the ability to control NP size together with targeted delivery may result in favorable biodistribution and development of clinically relevant targeted therapies.
1.3K
Magnetically Responsive Polymeric Microparticles for Oral Delivery of Protein Drugs
Jianjun Cheng,Benjamin A. Teply,Benjamin A. Teply,Seok Yoon Jeong,Christopher H. Yim,Dennis Ho,Ines Sherifi,Ines Sherifi,Sangyong Jon,Omid C. Farokhzad,Omid C. Farokhzad,Ali Khademhosseini,Ali Khademhosseini,Robert Langer +13 more
TL;DR: A substantially improved hypoglycemic effect was observed in mice that were orally administered with insulin–magnetite–PLGA microparticles in the presence of an external magnetic field, suggesting that magnetic force can be used to improve the efficiency of orally delivered protein therapeutics.
The use of charge-coupled polymeric microparticles and micromagnets for modulating the bioavailability of orally delivered macromolecules
Benjamin A. Teply,Rong Tong,Seok Yoon Jeong,Gaurav Luther,Ines Sherifi,Ines Sherifi,Christopher H. Yim,Ali Khademhosseini,Ali Khademhosseini,Omid C. Farokhzad,Omid C. Farokhzad,Robert Langer,Jianjun Cheng +12 more
TL;DR: A formulation strategy is developed that can be used to prolong intestinal retention of drug delivery vehicles without substantial alterations to current polymeric encapsulation strategies to allow for greater absorption and increased bioavailability of protein drugs.
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Anterior cruciate ligament surgery in the rabbit
TL;DR: An efficient and cost-effective model to study either native or tissue-engineered allografts for anterior cruciate ligament (ACL) replacement in a New Zealand rabbit model with the potential for transgenic and cell migration studies is described.