Inês Cabrito
Ablynx
13 Papers
33 Citations
Inês Cabrito is an academic researcher from Ablynx. The author has contributed to research in topics: Nitrous-oxide reductase & Macrophage migration inhibitory factor. The author has an hindex of 8, co-authored 13 publications. Previous affiliations of Inês Cabrito include Pharmaceutical Product Development & Universidade Nova de Lisboa.
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Papers
A genome-wide linkage and association scan reveals novel loci for autism
Lauren A. Weiss,Lauren A. Weiss,Dan E. Arking,Mark J. Daly,Mark J. Daly,Aravinda Chakravarti,Camille W. Brune,Kristen West,Ashley O'Connor,Gina Hilton,Rebecca L. Tomlinson,Andrew B. West,Edwin H. Cook,Todd Green,Shun-Chiao Chang,Stacey Gabriel,Casey Gates,Ellen M. Hanson,Andrew Kirby,Andrew Kirby,Joshua M. Korn,Joshua M. Korn,Finny G Kuruvilla,Finny G Kuruvilla,Steven A. McCarroll,Steven A. McCarroll,Eric M. Morrow,Eric M. Morrow,Eric M. Morrow,Benjamin M. Neale,Benjamin M. Neale,Shaun Purcell,Shaun Purcell,Roksana Sasanfar,Carrie Sougnez,Christine Stevens,David Altshuler,David Altshuler,James F. Gusella,James F. Gusella,Susan L. Santangelo,Pamela Sklar,Pamela Sklar,Rudolph E. Tanzi,Richard Anney,Anthony J. Bailey,Gillian Baird,Agatino Battaglia,Tom Berney,Catalina Betancur,Sven Bölte,Patrick Bolton,Jessica Brian,Susan E. Bryson,Joseph D. Buxbaum,Inês Cabrito,Guiqing Cai,Rita M. Cantor,Hilary Coon,Judith Conroy,Catarina Correia,Christina Corsello,Emily L. Crawford,Michael L. Cuccaro,Geraldine Dawson,Maretha de Jonge,Bernie Devlin,Eftichia Duketis,Sean Ennis,Annette Estes,Penny Farrar,Eric Fombonne,Christine M. Freitag,Louise Gallagher,Daniel H. Geschwind,John R. Gilbert,Michael Gill,Christopher Gillberg,Jeremy Goldberg,Andrew Green,Jonathan Green,Stephen J. Guter,Jonathan L. Haines,Joachim Hallmayer,Vanessa Hus,Sabine M. Klauck,Olena Korvatska,Janine A. Lamb,Magdalena Laskawiec,Marion Leboyer,Ann Le Couteur,Bennett L. Leventha,Xiao-Qing Liu,Catherine Lord,Linda Lotspeich,Elena Maestrini,Tiago R. Magalhaes,William M. Mahoney,Carine Mantoulan,Helen McConachie,Christopher J. McDougle,William M. McMahon,Christian R. Marshall,Judith Miller,Nancy J. Minshew,Anthony P. Monaco,Jeff Munson,John I. Nurnberger,Guiomar Oliveira,Alistair T. Pagnamenta,Katerina Papanikolaou,Jeremy R. Parr,Andrew D. Paterson,Margaret A. Pericak-Vance,Andrew Pickles,Dalila Pinto,Joseph Piven,David J. Posey,Annemarie Poustka,Fritz Poustka,Regina Regan,Jennifer Reichert,Katy Renshaw,Wendy Roberts,Bernadette Rogé,Michael Rutter,Jeff Salt,Gerard D. Schellenberg,Stephen W. Scherer,Val C. Sheffield,James S. Sutcliffe,Peter Szatmari,Katherine E. Tansey,Ann P. Thompson,John Tsiantis,Herman van Engeland,Astrid M. Vicente,Veronica J. Vieland,Fred R. Volkmar,Simon Wallace,Thomas H. Wassink,Ellen M. Wijsman,Kirsty Wing,Kerstin Wittemeyer,Brian L. Yaspan,Lonnie Zwaigenbaum,Seung Yun Yoo,Seung Yun Yoo,Seung Yun Yoo,Robert Sean Hill,Robert Sean Hill,Robert Sean Hill,Nahit Motavalli Mukaddes,Soher Balkhy,Generoso G. Gascon,Generoso G. Gascon,Samira Al-Saad,Asif Hashmi,Janice Ware,Robert M. Joseph,Elaine LeClair,Jennifer N. Partlow,Jennifer N. Partlow,Brenda E. Barry,Brenda E. Barry,Christopher A. Walsh,Christopher A. Walsh,Christopher A. Walsh,David L. Pauls,Irma Moilanen,Hanna Ebeling,Marja Leena Mattila,Sanna Kuusikko,Katja Jussila,Jaakko Ignatius,Ala Tolouei,Majid Ghadami,Maryam Rostami,Azam Hosseinipour,Maryam Valujerdi,Kara Andresen,Brian Winkloski,Stephen A. Haddad,Lou Kunkel,Zak Kohane,Tram Tran,Sek Won Kong,Stephanie Brewster O'Neil,Rachel J. Hundley,Ingrid A. Holm,Heather Peters,Elizabeth Baroni,Aislyn Cangialose,Lindsay Jackson,Lisa H. Albers,Ronald E. Becker,Carolyn Bridgemohan,Sandra L. Friedman,Kerim Munir,Ramzi Nazir,Judith S. Palfrey,Alison Schonwald,Esau Simmons,Leonard Rappaport,Julie Gauthier,Laurent Mottron,Ridha Joober,Guy A. Rouleau,Karola Rehnström,Karola Rehnström,Lennart von Wendt,Lennart von Wendt,Leena Peltonen,Leena Peltonen,Leena Peltonen +214 more
TL;DR: A linkage and association mapping study using half a million genome-wide single nucleotide polymorphisms in a common set of 1,031 multiplex autism families, implicating SEMA5A as an autism susceptibility gene.
Activation of N2O reduction by the fully reduced micro4-sulfide bridged tetranuclear Cu Z cluster in nitrous oxide reductase.
Somdatta Ghosh,Serge I. Gorelsky,Peng Chen,Inês Cabrito,José J. G. Moura,Isabel Moura,Edward I. Solomon +6 more
TL;DR: This study shows that the fully reduced 4CuI form of the cluster correlates with the catalytic activity of the enzyme nitrous oxide reductase, and is the first demonstration that the S = 1/2 form of CuZ can be further reduced.
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Purification, characterization, and preliminary crystallographic study of copper-containing nitrous oxide reductase from Pseudomonas nautica 617.
Miguel Prudêncio,Alice S. Pereira,Pedro Tavares,Stéphane Besson,Inês Cabrito,K. Brown,B Samyn,Bart Devreese,J. Van Beeumen,Frank Rusnak,G. Fauque,José J. G. Moura,M. Tegoni,C. Cambillau,Isabel Moura +14 more
TL;DR: The aerobic purification of Pseudomonas nautica 617 nitrous oxide reductase yielded two forms of the enzyme exhibiting different chromatographic behaviors, interpreted as a difference in the oxidation state of the Cu(A) center.
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Desulfoferrodoxin: a modular protein.
Carla Ascenso,Frank Rusnak,Inês Cabrito,Maria João Lima,Stephen Naylor,Isabel Moura,José J. G. Moura +6 more
TL;DR: The results are consistent with superoxide reductase activity and a possible explanation for the low superoxide consumption in the superoxide dismutase activity assays is proposed.
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Novel half-life extended anti-MIF nanobodies protect against endotoxic shock.
Amanda Sparkes,Amanda Sparkes,Patrick De Baetselier,Patrick De Baetselier,Lea Brys,Lea Brys,Inês Cabrito,Inês Cabrito,Yann G.-J. Sterckx,Steve Schoonooghe,Steve Schoonooghe,Serge Muyldermans,Geert Raes,Geert Raes,Richard Bucala,Peter Vanlandschoot,Jo A. Van Ginderachter,Jo A. Van Ginderachter,Benoit Stijlemans,Benoit Stijlemans +19 more
TL;DR: Nbs, with their structural and pharmacologic advantages over currently available inhibitors, may be an effective, novel approach to interfere with the action of MIF in septic shock and other conditions of inflammatory endorgan damage.
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