The article provides an overview of modern scientific approaches to assessing the state of neurofunctional activity of the brain under the professional influence of physical and chemical factors is presented, carried out using bibliographic databases Scopus, MedLine, Web of Science, PubMed, The Cochrane Library, RSCI, Cyberleninka, Google Academy, Index Copernicus, SJR, Science Direct, Arxiv.Org. The work reflects the results of research by domestic and foreign scientists stating the fact of violations of neurobioelectric activity, cerebral hemodynamics, afferent conductive structures, cytokine and neuropsychological status in patients with vibration disease, sensorineural hearing loss, chronic mercury intoxication. There are prospects for using neuroenergic mapping with registration of the level of constant potential. The effects of biofeedback training (biofeedback method) on the reference reaction in order to stabilize and activate the neurofunctional activity of the brain in the treatment of neurological patients are reflected. The analysis of literary sources allowed us to substantiate the need to use artificial intelligence technologies to automate processes as a highly sensitive and specific method of detecting occupational pathology. The presented data indicate the relevance of the problem of studying disorders of neurofunctional activity, the relationship between the nervous and immune systems under the influence of vibration, noise, metallic mercury to improve the criteria for diagnosing lesions of the central nervous system.

Modern ideas about the state of neurofunctional activity of the brain under the professional influence of physical and chemical factors

Occupational hearing loss in the civilian flight crew members prevails in the structure of occupational hearing loss. The study was aimed to assess errors made in forensic evaluation of flight personnel with hearing loss. A total of 213 definitive diagnoses of occupational hearing loss established in 2015–2021 were assessed. Expert errors were found in 73% of cases. The most common, typical errors were reported that were evident in 12 cases submitted for forensic evaluation. The main errors were as follows: incorrect assessment of the parameters of noise inside the aircraft cabin, lack of knowledge about the clinical and audiological features of noise-induced hearing loss, incorrect assessment of audiological indicators, underestimation of the role of comorbidities, etc. The findings showed that high proportion of occupational hearing loss in the civilian flight crew members was in large part due to imperfection of expert solutions resulting from the lack of knowledge about the basic criteria of the diagnosis and the relationship between the noise-induced hearing loss and profession. The major requirements for evaluation of the relationship between the noise-induced hearing loss and profession and the issues related to professional suitability set out in the current regulatory documents issued by the Ministry of Health of the Russian Federation and seminal publications were not taken into account. The cornerstones of expert work on the issues of the relationship between the hearing organ disorder and profession in the civilian flight crew members were underestimated. This resulted in unsubstantiated professional unsuitability, disability among working-age people, and economic losses.

Current issues of the occupational sensorineural hearing loss evaluation in airline pilots

Introduction. The structure and prevalence of occupational and occupational-related pathology largely depends on the level of non-compliance with sanitary and hygienic standards of the harmful factors of the working environment at industrial facilities, as well as the completeness and quality of mandatory preliminary and periodic medical examinations of employees. Occupational health is actively studying the relationship between the hygienic parameters of production and the clinical and physiological parameters of the body to assess the occupational risk of pathological changes in the health status of workers, and therefore an interdisciplinary approach to the study of this issue is extremely relevant.The study aims to provide scientific substantiation of methodological approaches to assessing the occupational risk of upper respiratory tract pathology in workers of caustic soda production.Materials and methods. The authors have studied the peculiarities of the health status of 292 employees of a caustic soda production company. The work uses a set of hygienic, clinical, laboratory, morphological, instrumental, and statistical research methods.Results. The risk of upper respiratory tract pathology among employees of a caustic soda production plant is determined by a chemical factor due to the predominant content of chlorine gas and metallic mercury in the air of the working area. Researchers have established the peculiarities of the formation of pathological processes in the mucous membrane of the upper respiratory tract and bronchopulmonary system in workers of caustic soda production, depending on the variants and combinations of the influencing chemicals.The study identified key indicators characterizing the effect of chemicals on the state of the respiratory tract. These include: a shift in the pH of nasal secretions to the alkaline side, a violation of the functional integrity of the epithelial layer of the upper respiratory tract, expressed in a decrease in its transport activity, as well as morphometric changes manifested in an increase in the index of alteration of ciliated and multilayered squamous epithelium, indicating a violation of the regulation of physiological processes in the respiratory system, which can have negative consequences for her general condition. Further research in this area may contribute to the development of effective strategies for the prevention and correction of the negative effects of exposure to industrial aerosols on the health of workers.Limitations. The study is limited to a sample of individuals from certain professional groups.Conclusion. The risk of developing upper respiratory tract pathology in employees of caustic soda enterprises is due to a chemical factor with a predominant content of chlorine gas and metallic mercury in the air of the work area. Based on the results of the study of functional and morphometric shifts in the upper respiratory tract, the authors identified approaches to early diagnosis, prediction of the development of respiratory pathology and minimization of negative consequences for the health of workers in professional contact with caustic soda chemicals.Ethics. The survey of employees was conducted in accordance with the Ethical standard of the Helsinki Declaration of the World Medical Association "Ethical principles of conducting scientific medical research with human participation". All the surveyed signed an informed consent to participate in the study. There is a conclusion of the Local Ethics Committee of theNational Medical Research Center for Otorhinolaryngology (Protocol No. 04/2016 dated 09/07/2016).Contributions:Fedina I.N. — concept and design of research, text editing;Uchurov A.G. — collection and processing of material, statistical data processing, writing text;Serebryakov P.V. — research design, statistical data processing, text editing;Bolshakov A.V. — material processing, statistical data processing, text writing;Fayzova Yu.M. — research concept, material processing;Pankova V.B. — research concept, text editing.Funding. The study had no funding.Conflict of interest. The authors declare no conflict of interest.Received: 21.10.2025 / Accepted: 12.11.2025 / Published: 10.12.2025

Assessment of occupational risk of upper respiratory tract pathology among caustic soda production workers

The voice is an important indicator of human health, since the state of voice function is related to the activity of the main body systems. Impaired vocal function significantly changes relationships with people for the worse, makes it difficult or completely impedes the performance of professional duties. The main causes of phonation-related diseases of the larynx, dysphonia, is a systematic overload of the voice.


OBJECTIVE
Analysis of modern regulations for the examination of the connection of the disease with the profession and professional suitability in diseases of the larynx.


MATERIAL AND METHODS
The analysis of existing and newly approved normative and methodological documents regulating expert work in determining the relationship of laryngeal disease with a profession and assessing professional suitability in workers of voice and speech professions has been carried out.


RESULTS
Diseases caused by an occupational factor are among the occupational diseases, the list of nosological forms of which is approved by the Ministry of Health of the Russian Federation. The procedure for the diagnosis of an occupational disease has been defined in two stages - preliminary and final diagnoses, and the necessary algorithms for the actions of specialists have been developed.


CONCLUSION
Strict consideration of all existing regulatory requirements for the examination of the relationship between the disease of the vocal apparatus and the profession and professional suitability of «voice professionals» is aimed at eliminating serious errors in detecting early symptoms of impaired vocal function, maintaining longevity, observing social justice and preserving the quality of life of employees and medical professionals.

[New regulations on the connection of voice disorders with the profession].

Introduction. The main tasks of the occupational pathology service are early diagnosis of occupational diseases, prevention of their formation, and in case of development, slowing down the progression. Due to the timely start of rehabilitation measures, it is possible to preserve employees' ability to work, and the employer — the labor potential of qualified personnel. 
In modern enterprises, it is necessary to create programs to provide workers with medical care at the early stages of the formation of diseases, to prevent their progression, the development of complications and the preservation of professional ability to work. 
The study aims are the scientific substantiation of methodological approaches to optimizing rehabilitation and preventive programs for employees of "dust−hazardous" professions. 
Materials and methods. The scientists have examined 254 employees of KAMAZ PJSC: 164 employees of the Foundry and 90 employees of other divisions of the enterprise. The work uses a complex of hygienic, clinical and laboratory, instrumental, statistical research methods. 
Results. The authors have established the features of the a priori and a posteriori risk of the formation of occupational pathology of the respiratory organs in the departments of a large machine-building enterprise. There is specificity of the development of respiratory pathology depending on the exposure characteristics and characteristics of the physico-chemical properties of industrial aerosols in workers of a machine-building enterprise. The researchers have developed and scientifically substantiated a methodological approach to the application of a set of measures aimed at reducing risk and preventing occupational pathology of the respiratory system in employees of a machine-building enterprise, based on a personalized assessment of harmful factors of the production environment, a differentiated approach to correcting modifiable risk factors. 
Conclusions. The authors justified the use of various rehabilitation and preventive programs for interned employees of the enterprise who have a high risk of developing occupational pathology of the respiratory system, developed a differentiated approach to the use of various rehabilitation and preventive programs based on the analysis of the dynamics of clinical and functional indicators reflecting the course of respiratory pathology under the influence of industrial aerosols of various compositions (formation of obstructive-restrictive disorders, changes in exercise tolerance, the dynamics of morbidity with temporary disability).

Development of rehabilitation and preventive programs for employees of "dust-hazardous" professions

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

IN Fedina

Author Tools

Chat about Author

Papers

Current issues of the occupational sensorineural hearing loss evaluation in airline pilots

Assessment of occupational risk of upper respiratory tract pathology among caustic soda production workers

[New regulations on the connection of voice disorders with the profession].

Development of rehabilitation and preventive programs for employees of "dust-hazardous" professions