Purpose: Prior to 90 Y radioembolization procedure a pretherapy simulation using 99m Tc-MAA 23 is performed. Alternatively, a small dosage of 90 Y microspheres could be used. We aimed to 24 assess the accuracy of lung shunt fraction (LSF) estimation in both high activity 90 Y 25 posttreatment and pretreatment scans with isotope activity of ~100 MBq, using different 26 imaging techniques. Additionally, we assessed the feasibility of visualising hot and cold 27 hepatic tumours in PET/CT and Bremsstrahlung SPECT/CT images. 28 Materials and Methods: Anthropomorphic phantom including liver (with two spherical 29 tumours) and lung inserts was filled with 90 Y chloride to simulate an LSF of 9.8%. The total 30 initial activity in the liver was 1451 MBq, including 19.4 MBq in the hot sphere. Nine 31 measurement sessions including PET/CT, SPECT/CT, and planar images were acquired at 32 activities in the whole phantom ranging from 1618 MBq down to 43 MBq. The visibility scores.

PET/CT and SPECT/CT imaging of 90 Y hepatic radioembolization at 2 therapeutic and diagnostic activity levels: anthropomorphic phantom study and SPECT/CT anthropomorphic phantom imaging

22 Purpose: Prior to 90 Y radioembolization procedure a pretherapy simulation using 99m Tc-MAA 23 is performed. Alternatively, a small dosage of 90 Y microspheres could be used. We aimed to 24 assess the accuracy of lung shunt fraction (LSF) estimation in both high activity 90 Y 25 posttreatment and pretreatment scans with isotope activity of ~100 MBq, using different 26 imaging techniques. Additionally, we assessed the feasibility of visualising hot and cold 27 hepatic tumours in PET/CT and Bremsstrahlung SPECT/CT images. 28 Materials and Methods: Anthropomorphic phantom including liver (with two spherical 29 tumours) and lung inserts was filled with 90 Y chloride to simulate an LSF of 9.8%. The total 30 initial activity in the liver was 1451 MBq, including 19.4 MBq in the hot sphere. Nine 31 measurement sessions including PET/CT, SPECT/CT, and planar images were acquired at 32 activities in the whole phantom ranging from 1618 MBq down to 43 MBq.

PET/CT and SPECT/CT imaging of 90 Y hepatic radioembolization at

: Recently proposed time-gated diffuse correlation spectroscopy (TG-DCS) has significant advantages compared to conventional continuous wave (CW)-DCS, but it is still in an early stage and clinical capability has yet to be established. The main challenge for TG-DCS is the lower signal-to-noise ratio (SNR) when gating for the deeper traveling late photons. Longer wavelengths, such as 1064 nm have a smaller effective attenuation coefficient and a higher power threshold in humans, which significantly increases the SNR. Here, we demonstrate the clinical utility of TG-DCS at 1064 nm in a case study on a patient with severe traumatic brain injury admitted to the neuro-intensive care unit (neuroICU). We showed a significant correlation between TG-DCS early ( ρ = 0.67) and late ( ρ = 0.76) gated against invasive thermal diffusion flowmetry. We also analyzed TG-DCS at high temporal resolution (50 Hz) to elucidate pulsatile flow data. Overall, this study demonstrates the first clinical translation capability of the TG-DCS system at 1064 nm using a superconducting nanowire single-photon detector.

First-in-clinical application of a time-gated diffuse correlation spectroscopy system at 1064 nm using superconducting nanowire single photon detectors in a neuro intensive care unit

: Experimental and theoretical studies of colloidal nanoparticles have primarily focused on accurate characterization and simulation of observable characteristics, such as resonant wavelength. In this paper, we tackle the optimal design of colloidal-nanoparticle ensembles: what is the largest possible per-volume optical cross-section, which designs might achieve them, and can such response be experimentally demonstrated? We combine theory and experiment to answer each of these questions. We derive general bounds on the maximum cross-sections per volume, and we apply an analytical antenna model to show that resonant nanorods should nearly achieve such bounds. We use a modified seed-mediated synthesis approach to synthesize ensembles of gold nanorods with small polydispersity, i.e., small variations in size and aspect ratio. Polydispersity is the key determinant of how closely such ensembles can approach their respective bounds yet is difficult to characterize experimentally without near-field measurements. We show that a certain “extinction metric,” connecting extinction cross-section per volume with the radiative efficiencies of the nanoparticles, offers a quantitative prediction of polydispersity via quantities that can be rapidly measured with far-field characterization tools. Our predictions apply generally across all plasmonic materials and offer a roadmap to the largest possible optical response of nanoparticle ensembles.

Towards maximum optical efficiency of ensembles of colloidal nanorods

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Iller

Author Tools

Chat about Author

Papers

PET/CT and SPECT/CT imaging of 90 Y hepatic radioembolization at 2 therapeutic and diagnostic activity levels: anthropomorphic phantom study and SPECT/CT anthropomorphic phantom imaging

PET/CT and SPECT/CT imaging of 90 Y hepatic radioembolization at

First-in-clinical application of a time-gated diffuse correlation spectroscopy system at 1064 nm using superconducting nanowire single photon detectors in a neuro intensive care unit

Towards maximum optical efficiency of ensembles of colloidal nanorods