Ilham Hogga
University of Geneva
5 Papers
339 Citations
Ilham Hogga is an academic researcher from University of Geneva. The author has contributed to research in topics: Bithorax complex & Chromatin. The author has an hindex of 5, co-authored 5 publications.
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Papers
Chromatin domain boundaries in the Bithorax complex
József Mihály,Ilham Hogga,Stéphane Barges,Mireille Galloni,Rakesh Mishra,Kirsten Hagstrom,Martin Muller,Paul Schedl,László Sipos,János Gausz,Henrik Gyurkovics,François Karch +11 more
TL;DR: Preliminary evidence is provided that Fab-7 is not a mere insulator like scs or the reiterated binding site for the SU(HW) protein, and howFab-7 functions to confine activating as well as repressive signals to the flanking regulatory domains is described.
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Transcription through the iab-7 cis-regulatory domain of the bithorax complex interferes with maintenance of Polycomb-mediated silencing.
Ilham Hogga,François Karch +1 more
TL;DR: The data suggest that transcription through a Polycomb-Response Element (PRE) interferes with the maintenance of a PolyComb repression complex.
120
Dissecting the regulatory landscape of the Abd-B gene of the bithorax complex.
József Mihály,Stéphane Barges,László Sipos,Robert K. Maeda,Fabienne Cléard,Ilham Hogga,Welcome Bender,Henrik Gyurkovics,François Karch +8 more
TL;DR: This paper extends the analysis of regulatory elements within the BX-C by describing a series of internal deficiencies that affect the Abd-B regulatory region and highlights four key features of the iab-5,iab-6 and iab -7 cis-regulatory region of Abd- B.
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In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element
TL;DR: Results help to reconcile the previously contradictory models on Fab-7 function and shed light on how a chromatin domain boundary and a nearby PRE concur in the setting up of the appropriate PS-specific expression of the Abd-B gene of the BX-C.
Replacement of Fab-7 by the gypsy or scs insulator disrupts long-distance regulatory interactions in the Abd-B gene of the bithorax complex
TL;DR: The results reveal that the Fab-7 boundary must have special properties that scs and gypsy lack, which allow it to function appropriately in BX-C regulation, and reveals that the insulating activity of gypsy (but not scs) is lost in the CNS.