Il-Whan Choi
Inje University
219 Papers
1K Citations
Il-Whan Choi is an academic researcher from Inje University. The author has contributed to research in topics: Biology & Chemistry. The author has an hindex of 38, co-authored 203 publications. Previous affiliations of Il-Whan Choi include Chonbuk National University & Pukyong National University.
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Papers
Cancer cell-associated cytoplasmic B7-H4 is induced by hypoxia through hypoxia-inducible factor-1α and promotes cancer cell proliferation.
TL;DR: It is demonstrated that hypoxia upregulates B7-H4 transcription in primary CD138(+) multiple myeloma cells and cancer cell lines and its role in cancer cell proliferation in a hypoxic tumor microenvironment.
Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300
Min-Jung Ryu,Munju Cho,Jie-Young Song,Yeon-Sook Yun,Il-Whan Choi,Dong-Eun Kim,Byeoung-Soo Park,Sangtaek Oh +7 more
TL;DR: It is suggested that curcumin derivatives inhibit the Wnt/beta-catenin pathway by decreasing the amount of the transcriptional coactivator p300.
Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1
Matharage Gayani Dilshara,Kyoung-Tae Lee,Rajapaksha Gedara Prasad Tharanga Jayasooriya,Chang-Hee Kang,Sang Rul Park,Yung Hyun Choi,Il-Whan Choi,Jin-Won Hyun,Weon-Young Chang,Yeon-Su Kim,Hak-Ju Lee,Gi-Young Kim +11 more
TL;DR: The data indicate that TIA suppresses the production of proinflammatory mediators such as NO and PGE2, as well as their regulatory genes, in LPS-stimulated BV2 microglial cells, by inhibiting PI3K/Akt-dependent NF-κB activity and enhancing Nrf2-mediated HO-1 expression.
Type I pig collagen enhances the efficacy of PEDF 34-mer peptide in a mouse model of laser-induced choroidal neovascularization.
Hyun Woong Kim,Kug-Hwan Roh,Seong Wook Kim,Sung Jae Park,Na-Young Lim,Hana Jung,Il-Whan Choi,Sae-Gwang Park +7 more
TL;DR: Pigment epithelium-derived factor (PEDF)–derived 34-mer peptide has anti-angiogenic activity but has limitations in clinical application because of an inverted bell–shaped dose-effect relationship and a short half-life, so this study attempted to mitigate these problems by mixing PEDF34 with type I collagen.
The muscarinic receptor antagonist tolterodine inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells.
Mi Seon Seo,Jin Ryeol An,Hee Seok Jung,Won-Kyo Jung,Il-Whan Choi,Sunghun Na,Hongzoo Park,Young Min Bae,Won Sun Park +8 more
TL;DR: It is concluded that tolterodine inhibits Kv channels in concentration-, time-, and use (state)-dependent manners, irrespective of its antagonism of muscarinic receptors.