Igor M. Paiva
University of Alberta
16 Papers
87 Citations
Igor M. Paiva is an academic researcher from University of Alberta. The author has contributed to research in topics: Micelle & Chemistry. The author has an hindex of 7, co-authored 15 publications. Previous affiliations of Igor M. Paiva include Universidade Federal de Juiz de Fora & Universidade Federal de Minas Gerais.
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Papers
Decoration of Anti-CD38 on Nanoparticles Carrying a STAT3 Inhibitor Can Improve the Therapeutic Efficacy Against Myeloma.
Yung-Hsing Huang,Mohammad Reza Vakili,Ommoleila Molavi,Ommoleila Molavi,Yuen Morrissey,Chengsheng Wu,Igor M. Paiva,Amir Hasan Soleimani,Forugh Sanaee,Afsaneh Lavasanifar,Raymond Lai +10 more
TL;DR: This study suggests that the decoration of anti-CD38 on NP loaded with STAT3 inhibitors can further improve their therapeutic effects against MM.
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Lactobacillus kefiranofaciens and Lactobacillus satsumensis isolated from Brazilian kefir grains produce alpha-glucans that are potentially suitable for food applications
Igor M. Paiva,R.S. Steinberg,Ivana Silva Lula,Elaine M. Souza-Fagundes,Thiago de Oliveira Mendes,Maria José Valenzuela Bell,Jacques Robert Nicoli,Álvaro Cantini Nunes,Elisabeth Neumann +8 more
TL;DR: This study suggests that these exopolysaccharides produced by novel Lactobacillus strains from Brazilian milk or sugar water kefir might be useful as food additives due to their safety features to the host.
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Synthesis and Analysis of 64Cu-Labeled GE11-Modified Polymeric Micellar Nanoparticles for EGFR-Targeted Molecular Imaging in a Colorectal Cancer Model
Igor M. Paiva,Stephanie Mattingly,Melinda Wuest,Samantha Leier,Mohammad Reza Vakili,Michael Weinfeld,Afsaneh Lavasanifar,Frank Wuest +7 more
TL;DR: The data suggest that the efficacy of image-guided therapies with micellar nanoparticles can be enhanced by active targeting, as demonstrated with cancer biomarker EGFR.
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Proteolytically Stable Cyclic Decapeptide for Breast Cancer Cell Targeting
Yogita Raghuwanshi,Hashem Etayash,Rania Soudy,Igor M. Paiva,Afsaneh Lavasanifar,Kamaljit Kaur,Kamaljit Kaur +6 more
TL;DR: Animal studies using mice carrying orthotopic breast MDA-MB-231 tumors showed that the cyclic peptide preferentially accumulates in tumor (2 h after injection) and is rapidly cleared from all other organs except kidneys and liver.
21
Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma.
Amir Soleimani,Shyam M. Garg,Igor M. Paiva,Mohammad Reza Vakili,Abdulraheem Alshareef,Yung-Hsing Huang,Ommoleila Molavi,Ommoleila Molavi,Raymond Lai,Afsaneh Lavasanifar +9 more
TL;DR: The findings show that both PCL- and PBCL-based polymeric micelles have potential for the solubilization and delivery of S3I-1757, a potent STAT3 inhibitory agent.
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