Igor Del Vecchio
University of Pavia
11 Papers
137 Citations
Igor Del Vecchio is an academic researcher from University of Pavia. The author has contributed to research in topics: Promoter & Gene. The author has an hindex of 8, co-authored 11 publications.
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Papers
Cognition enhancers between treating and doping the mind.
Cristina Lanni,Silvia C. Lenzken,Alessia Pascale,Igor Del Vecchio,Marco Racchi,Francesca Pistoia,Stefano Govoni +6 more
TL;DR: This review discusses some critical aspects of the different cerebral circuits and molecular events regulating memory, attention and creativity in order to outline the neurobiological bases of the effects of "smart drugs" on cognitive functions, and to evaluate their putative pharmaceutical development.
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Functional mapping of the promoter region of the GNB2L1 human gene coding for RACK1 scaffold protein.
Igor Del Vecchio,Annalisa Zuccotti,Federica Pisano,Fabio Canneva,Silvia C. Lenzken,Françoise Rousset,Emanuela Corsini,Stefano Govoni,Marco Racchi +8 more
TL;DR: It is hypothesize that the imbalance between DHEA and cortisol during aging could be important in the previously demonstrated recovery of the RACK1 expression, and modulated by distant elements (enhancers/silencers) or directly on the mapped GNB2L1 promoter.
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•Journal Article
Differential expression of the prion-like protein doppel gene (PRND) in astrocytomas: a new molecular marker potentially involved in tumor progression
Sergio Comincini,Angelica Facoetti,Igor Del Vecchio,Katell Peoc'h,Jean-Louis Laplanche,Lorenzo Magrassi,Mauro Ceroni,Luca Ferretti,Rosanna Nano +8 more
TL;DR: The findings suggest that the PRND gene might be a useful molecular marker in astrocytoma progression and in tumor grade definition and understanding of the mechanisms of PRND increased expression might provide insight into the regulatory pathways of glioma development.
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Prion-like Doppel gene (PRND) in the goat: genomic structure, cDNA, and polymorphisms.
Cristina Uboldi,Igor Del Vecchio,M.G. Foti,Alberto Azzalin,Marianna Paulis,Elena Raimondi,Gabriele Vaccari,Umberto Agrimi,Giovanni Di Guardo,Sergio Comincini,Luca Ferretti +10 more
TL;DR: None of the polymorphisms was significantly relatable to the TSE status, and the same result was obtained by the analysis of the combined haplotypes at the five major polymorphic sites, namely, T28C, C65T, A151G, G286A, and C385G.
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Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells.
Sergio Comincini,Laurent R. Chiarelli,Paola Zelini,Igor Del Vecchio,Alberto Azzalin,Agustina Arias,Valentina Ferrara,Paola Rognoni,Antonella Dipoto,Rosanna Nano,Giovanna Valentini,Luca Ferretti +11 more
TL;DR: An aberrant doppel gene expression pattern is suggested, characterized by a substantial nuclear retention of the transcript, an altered post-translational modification of the protein and an unusual cytoplasmic localization.
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