Iasha Chaudhry
University of British Columbia
4 Papers
Iasha Chaudhry is an academic researcher from University of British Columbia. The author has contributed to research in topics: Caenorhabditis elegans & Mutation. The author has an hindex of 4, co-authored 4 publications.
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Papers
The Million Mutation Project: A new approach to genetics in Caenorhabditis elegans
Owen Thompson,Mark L. Edgley,Pnina Strasbourger,Stephane Flibotte,Brent Ewing,Ryan Adair,Vinci Au,Iasha Chaudhry,Lisa Fernando,Harald Hutter,Armelle Kieffer,Joanne Lau,Norris Lee,Angela Miller,Greta Raymant,Bin Shen,Jay Shendure,Jon Taylor,Emily H. Turner,LaDeana W. Hillier,Donald G. Moerman,Robert H. Waterston +21 more
TL;DR: A nonsense suppressor is revealed as well as strains with higher levels of indels that harbor mutations in DNA repair genes and strains with abundant males associated with him mutations, providing an unprecedented genetic resource for this multicellular organism.
Large-scale screening for targeted knockouts in the caenorhabditis elegans genome
Robert Barstead,Gary Moulder,Beth L. Cobb,Stephen Frazee,Diane Henthorn,Jeff Holmes,Daniela Jerebie,Martin Landsdale,Jamie Osborn,Cherilyn Pritchett,James Robertson,John A. Rummage,Ed Stokes,Malani Vishwanathan,Shohei Mitani,Keiko Gengyo-Ando,Osamu Funatsu,Sayaka Hori,Rieko Imae,Eriko Kage-Nakadai,Hiroyuki Kobuna,Etsuko Machiyama,Tomoko Motohashi,Muneyoshi Otori,Yuji Suehiro,Sawako Yoshina,Donald G. Moerman,Mark L. Edgley,Ryan Adair,BJ Allan,Vinci Au,Iasha Chaudhry,Rene Cheung,Owen Dadivas,Simon Eng,Lisa Fernando,Angela Fisher,Stephane Flibotte,Erin J. Gilchrist,Allison Hay,Peter Huang,Rebecca Worsley Hunt,Christine Kwitkowski,Joanne Lau,Norris Lee,Lucy Liu,Adam Lorch,Candy Luck,Jason S. Maydan,Sheldon J. McKay,Angela Miller,Greg Mullen,Candice Navaroli,Sarah E. Neil,Rebecca Hunt-Newbury,Mikhaela Partridge,Jaryn D. Perkins,Anna Rankin,Greta Raymant,Nadereh Rezania,Alexandra Rogula,Bin Shen,Greg Stegeman,Angela Tardif,Jon Taylor,Mariana Veiga,Tina Wang,Rick Zapf +67 more
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Whole-Genome Profiling of Mutagenesis in Caenorhabditis elegans
Stephane Flibotte,Mark L. Edgley,Iasha Chaudhry,Jon Taylor,Sarah E. Neil,Aleksandra Rogula,Rick Zapf,Martin Hirst,Yaron S. Butterfield,Steven J.M. Jones,Marco A. Marra,Robert Barstead,Donald G. Moerman +12 more
TL;DR: The spectrum of mutations induced by three commonly used mutagens: ethyl methanesulfonate (EMS), N-ethyl-N-nitrosourea (ENU), and ultraviolet trimethylpsoralen (UV/TMP) in the nematode Caenorhabditis elegans is described and the strong GC to AT transition bias of EMS is confirmed.
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An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans.
Barbara Meissner,Adam Warner,Kim Wong,Nicholas Dube,Adam Lorch,Sheldon J. McKay,Jaswinder Khattra,Teresa M. Rogalski,Aruna Somasiri,Iasha Chaudhry,Rebecca M. Fox,David M. Miller,David L. Baillie,Robert A. Holt,Steven J.M. Jones,Marco A. Marra,Donald G. Moerman +16 more
TL;DR: It is proposed that additional sarcomeric proteins exist for which there is a less severe, or entirely different, mutant phenotype produced in their absence from late embryonic muscle gene expression.
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