Ian Tomlinson
University of Birmingham
649 Papers
4.7K Citations
Ian Tomlinson is an academic researcher from University of Birmingham. The author has contributed to research in topics: Cancer & Genome-wide association study. The author has an hindex of 119, co-authored 607 publications. Previous affiliations of Ian Tomlinson include Cancer Research UK & University of Cambridge.
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Papers
OC-059 Whole transcriptome analysis of colon cancer lymph node metastases reveals metastasis driver genes, signatures and effect of lymphoid ecological niche immune profile
TL;DR: A thorough understanding of the biological alterations involved in metastasis is important to improve and develop new therapies for patients with CRC, and use and validation of these biomarkers, particularly LNMS classifications may help predict outcomes for stage III CRCs.
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Erratum: Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia (vol 117, pg 1215, 2017)
Stephanie A. Schubert,Dina Ruano,Fadwa A. Elsayed,Arnoud Boot,Stijn Crobach,Arantza Farina Sarasqueta,Bruce H. R. Wolffenbuttel,Melanie M. van der Klauw,Jan Oosting,Carli M. J. Tops,Ronald van Eijk,Hans F. A. Vasen,Rolf H. A. M. Vossen,Maartje Nielsen,Sergi Castellví-Bel,Clara Ruiz-Ponte,Ian Tomlinson,Malcolm G. Dunlop,Pavel Vodicka,Juul T. Wijnen,Frederik J. Hes,Hans Morreau,Noel F C C de Miranda,Rolf H. Sijmons,Tom van Wezel +24 more
TL;DR: This book is dedicated to the memory of those who have served in the armed forces and their families during the conflicts of the Troubles.
Pregnancy does not influence colonic polyp multiplicity but may modulate upper gastrointestinal disease in patients with FAP
Nirosha Suraweera,Andrew Latchford,Amy McCart,Pauline Rogers,Sarah L. Spain,Oliver M. Sieber,Robin K. S. Phillips,Ian Tomlinson,Andrew Silver +8 more
TL;DR: The data suggest that reproduction may influence disease severity in the upper gastrointestinal tract in patients with FAP.
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High‐Resolution Breakpoint Analysis Provides Evidence for the Sequence‐Directed Nature of Genome Rearrangements in Hereditary Disorders
Michal Kovac,Michal Kovac,Michal Kovac,Monika Kovacova,Hynek Bachraty,Katarína Bachratá,Salvatore Piscuoglio,Salvatore Piscuoglio,Salvatore Piscuoglio,Pierre Hutter,Denisa Ilencikova,Zdena Bartosova,Ian Tomlinson,Benno Roethlisberger,Karl Heinimann,Karl Heinimann +15 more
TL;DR: This study first identified candidate motifs by studying 112 pathogenic germ‐line GRs in hereditary colorectal cancer patients, and subsequently created an algorithm, termed recombination type ratio, which correctly predicts the propensity of rearrangements with respect to homologous versus nonhomologous recombination events.
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